Detalle de: Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy
| Title | Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy |
| Abstract |
The available treatments for leishmaniasis are less than optimal due to inadequate efficacy, toxic side effects, and the emergence of resistant strains, clearly endorsing the urgent need for discovery and development of novel drug candidates. Ideally, these should act via an alternative mechanism of action to avoid cross-resistance with the current drugs. |
| Apa Reference | Sebastián-Pérez, V., Hendrickx, S., Munday, J. C., Kalejaiye, T., Martínez, A., Campillo, N. E., de Koning, H., Caljon, G., Maes, L., & Gil, C. (2018). Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy. Antimicrobial Agents and Chemotherapy, 62(10). 10.1128/aac.00603-18 |
| Doi | 10.1128/AAC.00603-18 |
| Publication Date | Oct 2018 |
| Publication Type | Article |
| Researcher | Ana Martínez |
| Ontology | Development |
| Research Groups | Translational Medicinal and Biological Chemistry |
| Tools |