Detalle de: The first enantioselective synthesis of palinurin
| Title | The first enantioselective synthesis of palinurin |
| Abstract |
The first enantioselective synthesis of palinurin has been accomplished starting from commercially available furaldehyde and (R)-methyl-3-hydroxy-2-methylpropionate; the key steps of the synthesis include the use of a chiral pyrrolidine to create the chiral tetronic moiety, and Horner-Wadsworth-Emmons, Wittig and Wittig-Horner reactions to construct the alkene units. |
| Apa Reference | Pérez, M., Pérez, D. I., Martínez, A., Castro, A., Gómez, G., & Fall, Y. (2009). The first enantioselective synthesis of palinurin. Chemical Communications, 22, 3252. 10.1039/b822679b |
| Doi | 10.1039/b822679b |
| Publication Date | 2009 |
| Publication Type | Article |
| Researcher | Ana Martínez |
| Ontology | |
| Research Groups | Translational Medicinal and Biological Chemistry |
| Tools |