Detalle de: Peripheral and Dual Binding Site Acetylcholinesterase Inhibitors: Implications in treatment of Alzheimer's Disease
| Title | Peripheral and Dual Binding Site Acetylcholinesterase Inhibitors: Implications in treatment of Alzheimer's Disease |
| Abstract |
Recently advances in understanding the molecular basis of Alzheimer's disease have led to the consideration of the relationship between cholinergic inhibitors and amyloid deposition as a new hypothesis for the future rational design of effective anti-Alzheimer drugs. In the present review, the non-cholinergic functions of acetylcholinesterase (AChE) and the therapeutic potential of peripheral and dual binding site AChE inhibitors in delaying the neurodegenerative process will be discussed. |
| Apa Reference | Castro, A., & Martinez, A. (2001). Peripheral and Dual Binding Site Acetylcholinesterase Inhibitors: Implications in treatment of Alzheimers Disease. Mini-Reviews in Medicinal Chemistry, 1(3), 267–272. 10.2174/1389557013406864 |
| Doi | 10.2174/1389557013406864 |
| Publication Date | 1 Sep 2001 |
| Publication Type | Article |
| Researcher | Ana Martínez |
| Ontology | Drug Discovery and design, Molecular Interactions/Docking |
| Research Groups | Translational Medicinal and Biological Chemistry |
| Tools |