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Detalle de: Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors

Title Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors
Abstract

Modifications of our previously reported lead compounds, acyclonucleosides derived from 2,1,3-benzothiadiazine dioxides, in the search for inhibitors of human cytomegalovirus (HCMV), lead us to identify the chlorophenylmethyl benzothiadiazine dioxides derivatives as potent HCMV inhibitors. The synthesis and antiviral data of this second-generation of benzothiadiazine dioxide compounds are reported.

Apa Reference Martinez, A., Gil, C., Perez, C., Castro, A., Prieto, C., & Otero, J. (1999). Chlorophenylmethyl benzothiadiazine dioxides derivatives: Potent human cytomegalovirus inhibitors. Bioorganic & Medicinal Chemistry Letters, 9(21), 3133–3136. 10.1016/s0960-894x(99)00538-7
Doi 10.1016/S0960-894X(99)00538-7
Publication Date Nov 1999
Publication Type Article
Researcher Ana Martínez
Ontology Drug Discovery and design
Research Groups Translational Medicinal and Biological Chemistry
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