Detalle de: Imidazothiadiazine dioxides: Synthesis and antiviral activity
| Title | Imidazothiadiazine dioxides: Synthesis and antiviral activity |
| Abstract |
A new series of imidazothiadiazine dioxides, including the first acyclonucleosides derived from this heterocycle moiety, has been synthesized. A wide-spectrum antiviral screening was performed. Some of the N-1 benzyl imidazothiadiazines and the new acyclonucleosides showed interesting anti-CMV or anti-HIV activity. These structures could be considered as new lead compounds for antiviral drug research. |
| Apa Reference | Martı́nez, A., Esteban, A. I., Herrero, A., Ochoa, C., Andrei, G., Snoeck, R., Balzarini, J., & Clercq, E. D. (1999). Imidazothiadiazine dioxides: synthesis and antiviral activity. Bioorganic & Medicinal Chemistry, 7(8), 1617–1623. 10.1016/s0968-0896(99)00114-5 |
| Doi | 10.1016/S0968-0896(99)00114-5 |
| Publication Date | Aug 1999 |
| Publication Type | Article |
| Researcher | Ana Martínez |
| Ontology | Drug Discovery and design |
| Research Groups | Translational Medicinal and Biological Chemistry |
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