Detalle de: Synthesis and cytostatic screening of an SO2 analogue of doridosine

Imidazo[4,5‐ c ][1,2,6]thiadiazine ribosides have been prepared from furazano[3,4‐ c ][1,2,6]thiadiazine 5,5‐dioxides in a reaction sequence which involves introduction of the glycosidic rest, reductive cleavage of the furazan ring and cyclization. The ribosides were screened against HeLa cell cultures but showed no significant activity.