Detalle de: Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice
| Title | Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice |
| Abstract |
Key Points Crebbp inactivation perturbs B-cell development, but cooperates with Bcl2 overexpression to promote lymphoma. Transcriptional and epigenetic signatures of Crebbp loss implicate Myc in disease etiology. |
| Apa Reference | García-Ramírez, I., Tadros, S., González-Herrero, I., Martín-Lorenzo, A., Rodríguez-Hernández, G., Moore, D., Ruiz-Roca, L., Blanco, O., Alonso-López, D., Rivas, J.D.L., Hartert, K., Duval, R., Klinkebiel, D., Bast, M., Vose, J., Lunning, M., Fu, K., Greiner, T., Rodrigues-Lima, F., Jiménez, R., Criado, F.J.G., Cenador, M.B.G., Brindle, P., Vicente-Dueñas, C., Alizadeh, A., Sánchez-García, I. & Green, M.R. (2017). Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice. Blood, 129(19), 2645-2656. 10.1182/blood-2016-08-733469 |
| Doi | 10.1182/blood-2016-08-733469 |
| Publication Date | 11 May 2017 |
| Publication Type | Article |
| Researcher | Javier De Las Rivas |
| Ontology | Epigenomics, Development |
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