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Detalle de: Synthesis of New N-(4-Pyridyl)-1-aminopyrazoles and Their Muscarinic and Adrenergic Properties

Title Synthesis of New N-(4-Pyridyl)-1-aminopyrazoles and Their Muscarinic and Adrenergic Properties
Abstract

The synthesis of new N-(4-pyridyl)-1-aminopyrazoles is described. Their binding properties were tested for muscarinic and other neurotransmitter receptors, together with their acetylcholinesterase inhibitory activity. The series derived from 3,5-dimethyl-1H- pyrazole showed moderate activities in both muscarinic and adrenergic receptor binding tests

Apa Reference Rodríguez-Franco, M.I., Dorronsoro, I., Martínez, A., Pérez, C., Badía, A. & Ban˜os, J.E. (2000). Synthesis of New N-(4-Pyridyl)-1-aminopyrazoles and Their Muscarinic and Adrenergic Properties. Archiv der Pharmazie, 333(5), 118-122. 10.1002/(SICI)1521-4184(20005)333:5<118::AID-ARDP118>3.3.CO;2-H
Doi 10.1002/(SICI)1521-4184(20005)333:5<118::AID-ARDP118>3.3.CO;2-H
Publication Date May 2000
Publication Type Article
Researcher Ana Martínez
Ontology Molecular Interactions/Docking
Research Groups
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