Detalle de: Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy
| Title | Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy |
| Abstract |
Single-particle analysis by electron microscopy is a well established technique for analyzing the three-dimensional structures of biological macromolecules. Besides its ability to produce high-resolution structures, it also provides insights into the dynamic behavior of the structures by elucidating their conformational variability. Here, the different image-processing methods currently available to study continuous conformational changes are reviewed. |
| Apa Reference | Sorzano, C.O.S., Jiménez, A., Mota, J., Vilas, J.L., Maluenda, D., Martínez, M., Ramírez-Aportela, E., Majtner, T., Segura, J., Sánchez-García, R., Rancel, Y., del Caño, L., Conesa, P., Melero, R., Jonic, S., Vargas, J., Cazals, F., Freyberg, Z., Krieger, J., Bahar, I., Marabini, R. & Carazo, J.M. (2019). Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy. Acta Crystallographica Section F Structural Biology Communications, 75(1), 19-32. 10.1107/s2053230x18015108 |
| Doi | 10.1107/s2053230x18015108 |
| Publication Date | 1 Jan 2019 |
| Publication Type | Article |
| Researcher | Jose María Salvador Carazo Garcia |
| Ontology | Experimental structure determination, Molecular flexibility, Cryo-electron microscopy |
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