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Detalle de: Phylogenetic Reconstruction Using an Unsupervised Growing Neural Network That Adopts the Topology of a Phylogenetic Tree

Title Phylogenetic Reconstruction Using an Unsupervised Growing Neural Network That Adopts the Topology of a Phylogenetic Tree
Abstract

We propose a new type of unsupervised, growing, self-organizing neural network that expands itself by following the taxonomic relationships that exist among the sequences being classified. The binary tree topology of this neutral network, contrary to other more classical neural network topologies, permits an efficient classification of sequences. The growing nature of this procedure allows to stop it at the desired taxonomic level without the necessity of waiting until a complete phylogenetic tree is produced. This novel approach presents a number of other interesting properties, such as a time for convergence which is, approximately, a lineal function of the number of sequences. Computer simulation and a real example show that the algorithm accurately finds the phylogenetic tree that relates the data. All this makes the neural network presented here an excellent tool for phylogenetic analysis of a large number of sequences.

Apa Reference Dopazo, J. & Carazo, J.M. (1997). Phylogenetic Reconstruction Using an Unsupervised Growing Neural Network That Adopts the Topology of a Phylogenetic Tree. Journal of Molecular Evolution, 44(2), 226-233. 10.1007/pl00006139
Doi 10.1007/pl00006139
Publication Date Feb 1997
Publication Type Article
Researcher Jose María Salvador Carazo Garcia
Ontology Artificial Intelligence, Computational models and simulations, Phylogenetic Analysis, Deep Learning in Biology
Research Groups
Tools

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