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Detalle de: Fluorinated trehalose analogues for cell surface engineering and imaging of Mycobacterium tuberculosis

Title Fluorinated trehalose analogues for cell surface engineering and imaging of Mycobacterium tuberculosis
Abstract

The mycobacterial trehalose LpqY-SugABC ATP-binding cassette (ABC) transporter was hijacked to import fluorine-modified trehalose analogues to label cell-surface glycolipids and directly visualise the Mycobacterium tuberculosis pathogen by Focused Ion Beam (FIB) Secondary Ion Mass Spectrometry.

Apa Reference Guy, C.S., Gott, J.A., Ramírez-Cárdenas, J., de Wolf, C., Furze, C.M., West, G., Muñoz-García, J.C., Angulo, J. & Fullam, E. (2024). Fluorinated trehalose analogues for cell surface engineering and imaging of Mycobacterium tuberculosis. Chemical Science, 15(34), 13966-13975. 10.1039/d4sc00721b
Doi 10.1039/d4sc00721b
Publication Date 2024
Publication Type Article
Researcher Juan Carlos Muñoz García
Ontology
Research Groups
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