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Detalle de: From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe

Title From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe
Abstract

High‐quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample‐handling procedures leading up to nucleic acid sequencing, covering tasks such as ensuring ethical and legal compliance, verifying accurate species identification, maintaining sample integrity during transport, and isolating high‐quality DNA or nuclei. While many of the challenges and solutions we discuss are broadly relevant, our regulatory and logistical examples are primarily from Europe. By synthesising practical guidance, we highlight the crucial importance of taxonomic expertise, proper vouchering and biobanking, rigorous cold‐chain management or alternative preservation methods, and emphasise adherence to packaging and shipping requirements for biological materials. We showcase examples spanning diverse regions, taxa and source materials, which underscore the importance of context‐specific strategies and internationally harmonised protocols, particularly for metadata reporting. Our recommendations aim to support both small‐scale projects and large initiatives, directing collective efforts to facilitate efficient sampling, vouchering and sample processing for future genomic studies.

Apa Reference Reichel, K., Pohjoismäki, J., Astrin, J.J., Böhne, A., Bortoluzzi, C., Bužan, E., del Campo, J., Ciofi, C., Di‐Nizo, C.B., Divakar, P.K., Greve, C., Hampl, V., Hilgers, L., Laine, V.N., Leonard, J.A., Lozano‐Fernandez, J., Lukić Bilela, L., Mazzoni, C.J., McCartney, A.M., Melo‐Ferreira, J., Monteiro, R., Oomen, R.A., Pavlek, M., Pimenta, J., Rindos, M., Seehausen, O., Tarieiev, A., Tomasello, S., Vinnere Pettersson, O., Waterhouse, R.M., Weber, A.A., Zinenko, O. & de Guttry, C. (2026). From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe. Molecular Ecology Resources, 26(2). 10.1111/1755-0998.70100
Doi 10.1111/1755-0998.70100
Publication Date 20 Jan 2026
Publication Type Article
Researcher Javier del Campo
Ontology Genomics, Genome Assembly
Research Groups
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