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Detalle de: proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes

Title proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes
Abstract

The interpretation of genomic, transcriptomic and other microbial ‘omics data is highly dependent on the availability of well-annotated genomes. As the number of publicly available microbial genomes continues to increase exponentially, the need for quality control and consistent annotation is becoming critical. We present proGenomes3, a database of 907 388 high-quality genomes containing 4 billion genes that passed stringent criteria and have been consistently annotated using multiple functional and taxonomic databases including mobile genetic elements and biosynthetic gene clusters. proGenomes3 encompasses 41 171 species-level clusters, defined based on universal single copy marker genes, for which pan-genomes and contextual habitat annotations are provided. The database is available at http://progenomes.embl.de/

Apa Reference Fullam, A., Letunic, I., Schmidt, T.S.B., Ducarmon, Q.R., Karcher, N., Khedkar, S., Kuhn, M., Larralde, M., Maistrenko, O.M., Malfertheiner, L., Milanese, A., Rodrigues, J.F.M., Sanchis-López, C., Schudoma, C., Szklarczyk, D., Sunagawa, S., Zeller, G., Huerta-Cepas, J., von Mering, C., Bork, P. & Mende, D.R. (2022). proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes. Nucleic Acids Research, 51(D1), D760-D766. 10.1093/nar/gkac1078
Doi 10.1093/nar/gkac1078
Publication Date 21 Nov 2022
Publication Type Article
Researcher Jaime Huerta Cepas
Ontology Omics, Transcriptomics, Genomics, Biological Databases, Genomic Annotation, Comparative Genomics
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