Detalle de: Linking extracellular survival signals and the apoptotic machinery
| Title | Linking extracellular survival signals and the apoptotic machinery |
| Abstract |
The survival of cells in multicellular organisms requires continuous stimulation from the extracellular environment. The phosphatidylinositol-3' kinase/Akt signaling cascade has been identified as a critical pathway for the transduction of extracellular survival signals. The finding that the pro-apoptotic protein BAD is a substrate of Akt/PKB has provided the first link between extracellular survival signals and the apoptotic machinery. |
| Apa Reference | Nuñez, G. & del Peso, L. (1998). Linking extracellular survival signals and the apoptotic machinery. Current Opinion in Neurobiology, 8(5), 613-618. 10.1016/s0959-4388(98)80089-5 |
| Doi | 10.1016/s0959-4388(98)80089-5 |
| Publication Date | Oct 1998 |
| Publication Type | Article |
| Researcher | Luis del Peso Ovalle |
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