Detalle de: Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study
| Title | Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study |
| Abstract |
A direct connection between the PAZ/3′-overhang binding affinity and the siRNA potency and specificity is defined through complementary experimental and computational results. |
| Apa Reference | Alagia, A., Jorge, A.F., Aviñó, A., Cova, T.F.G.G., Crehuet, R., Grijalvo, S., Pais, A.A.C.C. & Eritja, R. (2018). Exploring PAZ/3′-overhang interaction to improve siRNA specificity. A combined experimental and modeling study. Chemical Science, 9(8), 2074-2086. 10.1039/C8SC00010G |
| Doi | 10.1039/C8SC00010G |
| Publication Date | 2018 |
| Publication Type | Article |
| Researcher | Ramon Crehuet Simón |
| Ontology | Molecular Interactions/Docking, Non-coding RNA |
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