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Detalle de: Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified d-phenylalanine residues

Title Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified d-phenylalanine residues
Abstract

The synthesis of new analogues of the cationic antimicrobial peptide gramicidin S, having a modified D-phenylalanine residue, their antibacterial properties against several gram positive and negative strains, as well as their hemolytic activity is reported.

Apa Reference van der Knaap, M., Engels, E., Busscher, H.J., Otero, J.M., Llamas-Saiz, A.L., van Raaij, M.J., Mars-Groenendijk, R.H., Noort, D., van der Marel, G.A., Overkleeft, H.S. & Overhand, M. (2009). Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified d-phenylalanine residues. Bioorganic & Medicinal Chemistry, 17(17), 6318-6328. 10.1016/J.BMC.2009.07.042
Doi 10.1016/J.BMC.2009.07.042
Publication Date Sep 2009
Publication Type Article
Researcher Mark van Raaij
Ontology Drug Discovery and design
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