Detalle de: Pharmacological Elevation of Cellular Dihydrosphingomyelin Provides a Novel Antiviral Strategy against West Nile Virus Infection
| Title | Pharmacological Elevation of Cellular Dihydrosphingomyelin Provides a Novel Antiviral Strategy against West Nile Virus Infection |
| Abstract |
The flavivirus life cycle is strictly dependent on cellular lipid metabolism. Polyphenols like gallic acid and its derivatives are promising lead compounds for new therapeutic agents as they can exert multiple pharmacological activities, including the alteration of lipid metabolism. |
| Apa Reference | Jiménez de Oya, N., San-Félix, A., Casasampere, M., Blázquez, A., Mingo-Casas, P., Escribano-Romero, E., Calvo-Pinilla, E., Poderoso, T., Casas, J., Saiz, J., Pérez-Pérez, M. & Martín-Acebes, M.A. (2023). Pharmacological Elevation of Cellular Dihydrosphingomyelin Provides a Novel Antiviral Strategy against West Nile Virus Infection. Antimicrobial Agents and Chemotherapy, 67(4). 10.1128/aac.01687-22 |
| Doi | 10.1128/aac.01687-22 |
| Publication Date | 18 Apr 2023 |
| Publication Type | Article |
| Researcher | Patricia Mingo Casas |
| Ontology | Drug Discovery and design |
| Research Groups | |
| Tools |