Detalle de: Lower trabecular bone score in type 2 diabetes mellitus: A role for fat mass and insulin resistance beyond hyperglycaemia
| Title | Lower trabecular bone score in type 2 diabetes mellitus: A role for fat mass and insulin resistance beyond hyperglycaemia |
| Abstract |
Aims To examine the clinical and biochemical determinants of trabecular bone score (TBS) in type 2 diabetes mellitus (T2DM) patients. Methods Cross-sectional observational study in 137 T2DM patients (49-85 years). Whole-body fat percentage was estimated using the relative fat mass (RFM) equation. Bone mineral density (BMD) and TBS were assessed using dual-energy X-ray absorptiometry and TBS iNsight Software respectively. Results T2DM patients showed significantly lower TBS values (P Conclusions The adiposity estimated by RFM may negatively affect TBS and this relationship may be influenced by insulin resistance and SHBG. RFM could act as a key estimator of degraded bone microarchitecture risk in the T2DM population. |
| Apa Reference | Hayón-Ponce, M., García-Fontana, B., Avilés-Pérez, M.D., González-Salvatierra, S., Andújar-Vera, F., Moratalla-Aranda, E. & Muñoz-Torres, M. (2021). Lower trabecular bone score in type 2 diabetes mellitus: A role for fat mass and insulin resistance beyond hyperglycaemia. Diabetes & Metabolism, 47(6), 101276. 10.1016/j.diabet.2021.101276 |
| Doi | 10.1016/j.diabet.2021.101276 |
| Publication Date | Nov 2021 |
| Publication Type | Article |
| Researcher | Francisco Andújar Vera |
| Ontology | Bioinformatics Software and Tools |
| Research Groups | |
| Tools |