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Research Group

Detalle de: Epigenetic Complexes in Plant Immunity

Title Epigenetic Complexes in Plant Immunity
Description

[EN] It has been known for nearly a century that plants can develop immunity to viruses that they have previously encountered. Plants, however, do not have distinct mobile immune cells like animals. Understanding the process of adaptive immunity in plants is critical for translational research and applications. We combine classical virology techniques, with genetics, molecular biology and systems biology to identify plant immunity genes that are subjected to chromatin regulation during the infection. Those genes can usually recall previous stress events and be primed for a quicker response against subsequent environmental stimuli. The edition of chromatin marks in selected candidates may open new interesting and innovative biotechnological tools to engineer pathogen resistant plants.

[ES] Se sabe desde hace casi un siglo que las plantas pueden desarrollar inmunidad frente a virus que han encontrado previamente. Sin embargo, las plantas no poseen células inmunitarias móviles distintas como los animales. Comprender el proceso de inmunidad adaptativa en las plantas es fundamental para la investigación traslacional y sus aplicaciones. Combinamos técnicas clásicas de virología con genética, biología molecular y biología de sistemas para identificar genes de inmunidad vegetal que están sujetos a regulación por cromatina durante la infección. Estos genes suelen ser capaces de recordar eventos de estrés previos y estar preparados para una respuesta más rápida frente a estímulos ambientales posteriores. La edición de marcas de cromatina en candidatos seleccionados podría abrir nuevas herramientas biotecnológicas interesantes e innovadoras para diseñar plantas resistentes a patógenos.

Home Page https://www.i2sysbio.es/groups/24/
Contact Email r.correa@csic.es
Collaborating Companies
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Hpc Resources
Institution I2SYSBIO
Ontology
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Service Units
Research Lines Chromatin regulation of plant immunity, Epigenetic memory and priming in plant immunity, Chromatin editing for pathogen-resistant plants
Funded Projects The Role of Host Epigenetic Complexes on Plant Virus Evolution
Selected Publications
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Researchers Miriam Caballero Cerveró

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