Detalle de: Bacteria-instructed lymphocytes for cancer immunotherapy

Novel immunotherapies based on the ability of bacteria to modify immune responses: CD4+ T cells that capture bacteria by transphagocytosis become potent antigen-presenting cells able to activate cytotoxic CD8+ T cells, and B cells can also be instructed by bacteria. Mice treated with these cells after capturing bacteria expressing a tumor antigen were protected against tumor development.