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Detalle de: Transcription-replication conflicts and genome stability

Title Transcription-replication conflicts and genome stability
Description

Molecular mechanisms that maintain eukaryotic genome stability during DNA replication when the replication and transcription machineries collide (transcription-replication conflicts), stalling replication forks and accumulating R-loops, a cause of neurodegeneration and cancer. Biochemical, biophysical, cellular and structural techniques.

Research Groups Transcription-Replication Conflicts in Eukaryotes
Researchers Esther Ortega Portero

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