Detalle de: Viral protease-mediated evasion of antiviral immunity

Molecular mechanisms by which RNA viruses counteract the host type-I interferon response, using foot-and-mouth disease virus (FMDV) as a model: identification of host innate effector proteins targeted by the viral proteases Lpro and 3Cpro, such as the dual cleavage of the RIG-I-like sensors LGP2 and MDA5 and the degradation of cGAS.