Álvaro Chiner-Oms
Genomic of (Re)Emerging Pathogens · FISABIO
Biography
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I have a mixed academic background: on the one hand I studied a Technical Engineering in Computer Science (2007) and later a Degree in Biology (2013), as well as a Master's in Bioinformatics (2015). This mixed training has allowed me to specialize in the use of a wide range of computational techniques and bioinformatics tools. I obtained an FPU contract (2014) to carry out my doctoral thesis at the University of Valencia, studying the Mycobacterium tuberculosis complex (MTBC). During my PhD, I spent 3 months (2017) in United Kingdom, at the London School of Hygiene and Tropical Medicine, hosted by Teresa Cortés’ group. After defending my thesis, in 2019 I began a postdoctoral stage at the Institute of Biomedicine of Valencia (IBV-CSIC), hired under a European project at the Tuberculosis Genomics Unit (IP Dr. Iñaki Comas). There, I continued my research on the molecular evolution of the MTBC and taking responsibility for the bioinformatics structure of the unit. During the COVID-19 pandemic (2020), I was part of the main core of the SeqCOVID-Spain consortium. Due to the work developed in SARS-CoV-2, I was offered a permanent contract at the IBV-CSIC (2020). My doctoral thesis obtained an extraordinary doctorate award (2021), and I was also the first classified in the 16th edition of the 'Ciutat d'Algemesí Scientific-Technical Award', in the Consolidated Young Researcher category (2021). I’ve recently joined the FISABIO-Salud Pública Foundation with a Ramón y Cajal contract (2021 call, shift for young doctors) to start my own research group. I have taught in the Department of Genetics at the University of Valencia for the Degree in Biology, as well as in the Master's Degree in Bioinformatics at the University of Valencia (148 hours to date, from 2015 to 2022). I have also been involved in the organization and teaching of 5 editions of the FISABIO Summer School (from 2016 to 2021) and the workshop 'Bioinformatic tools in TB genomics: pathogen diversity & host transcriptomics' organized by the Spanish Research Network on Mycobacteria (2021 ). I have also co-authored two popular articles in The Conversation magazine, one of them having more than 300,000 readings, 218 tweets and 5633 recommendations on social networks. I have participated as a member of evaluation committees of two evaluation agencies, ANECA (2019 and 2022) and Aqu Catalunya (2018 and 2019), in the evaluation and accreditation processes of doctoral programs in the biomedicine branch of 5 different Spanish universities. |
Profile
| Institution | FISABIO |
| Position | Ramón y Cajal Researcher |
| Home page | https://fisabio.portalinvestigacion.com/investigadores/1415 |
| Contact email | achiner@fisabio.es |
| ORCID | 0000-0002-0463-0101 |
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Funded projects 1
Publications 39 entries
- Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project Article · 12 Aug 2024
- The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes Article · 11 Dec 2023
- Genomic approaches to tuberculosis management and control Book / chapter · 1 Sep 2023
- Selective Pressure by Rifampicin Modulates Mutation Rates and Evolutionary Trajectories of Mycobacterial Genomes Article · 17 Aug 2023
- Tracking SARS-CoV-2 introductions in Mozambique using pandemic-scale phylogenies: a retrospective observational study Article · Jun 2023
View all (34 more)
- Epidemiological and Genomic Analysis of a Large SARS-CoV-2 Outbreak in a Long-Term Care Facility in Catalonia, Spain Article · 21 Dec 2022
- The mineralocorticoid receptor modulates timing and location of genomic binding by glucocorticoid receptor in response to synthetic glucocorticoids in keratinocytes Article · 17 Dec 2022
- Genomic analysis of Mycobacterium brumae sustains its nonpathogenic and immunogenic phenotype Preprint · 2 Dec 2022
- Fine-grain population structure and transmission patterns of Mycobacterium tuberculosis in southern Mozambique, a high TB/HIV burden area Article · 29 Jul 2022
- Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection Article · 22 Apr 2022
- Spatial and temporal distribution of SARS-CoV-2 diversity circulating in wastewater Article · Mar 2022
- SARS-CoV-2 Outbreak on a Spanish Mink Farm: Epidemiological, Molecular, and Pathological Studies Article · 21 Jan 2022
- Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes Article · 24 Dec 2021
- An evolutionary functional genomics approach identifies novel candidate regions involved in isoniazid resistance in Mycobacterium tuberculosis Article · 24 Nov 2021
- Expanded tracking of a Beijing Mycobacterium tuberculosis strain involved in an outbreak in France Article · Nov 2021
- Complete Analysis of the Epidemiological Scenario around a SARS-CoV-2 Reinfection: Previous Infection Events and Subsequent Transmission Article · 27 Oct 2021
- Integrative transnational analysis to dissect tuberculosis transmission events along the migratory route from Africa to Europe Article · 5 Apr 2021
- Overlapping prison/community tuberculosis outbreaks in Costa Rica revealed by alternative analysis of suboptimal material Article · 31 Mar 2021
- Evolutionary and phenotypic characterization of spike mutations in a new SARS-CoV-2 Lineage reveals two Variants of Interest Preprint · 12 Mar 2021
- Detection Of Genomic Variants Of SARS-CoV-2 Circulating In Wastewater By High-Throughput Sequencing Preprint · 10 Feb 2021
- Recurrences of multidrug‐resistant tuberculosis: Strains involved, within‐host diversity, and fine‐tuned allocation of reinfections Article · 17 Jan 2021
- The first wave of the Spanish COVID-19 epidemic was associated with early introductions and fast spread of a dominating genetic variant Preprint · 22 Dec 2020
- Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor Article · 3 Nov 2020
- Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production Article · 23 Apr 2020
- Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections Article · 17 Feb 2020
- Specificity and mutagenesis bias of the mycobacterial alternative mismatch repair analyzed by mutation accumulation studies Article · 14 Feb 2020
- Towards next-generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics Article · 3 Oct 2019
- Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex Article · 5 Sep 2019
- Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species Article · 27 Aug 2019
- Large genomics datasets shed light on the evolution of the Mycobacterium tuberculosis complex Article · Aug 2019
- Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex Article · Jun 2019
- Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis Article · 15 Apr 2019
- Simplified Model to Survey Tuberculosis Transmission in Countries Without Systematic Molecular Epidemiology Programs Article · Mar 2019
- Whole genome sequencing–based analysis of tuberculosis (TB) in migrants: rapid tools for cross-border surveillance and to distinguish between recent transmission in the host country and new importations Article · 24 Jan 2019
- GENOMIC EPIDEMIOLOGY OF TUBERCULOSIS: FROM WITHIN HOST EVOLUTION TO GLOBAL MIGRATION PATTERNS Article · 30 Dec 2018
- Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase Article · 18 Oct 2018
- Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity Article · 28 Feb 2018
- Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts Article · 19 Jan 2018
- EvalMSA: A Program to Evaluate Multiple Sequence Alignments and Detect Outliers Article · Jan 2016
