Héctor Garcia Seisdedos
Structural Systems Biology · IBMB
Biography
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Hector graduated in Biology and Biochemistry from the University of Salamanca in 2007. He then moved to the Physical-Chemistry Department of the University of Granada to carry out his Ph.D. under the supervision of Beatriz Ibarra-Molero and Jose Manuel Sanchez-Ruiz. In his doctoral work, he combined experimental and bioinformatics to design tailor-made enzymes. After earning his Ph.D. in 2012, Hector joined Emmanuel Levy’s Lab as a postdoc at the Weizmann Institute of Science in 2013, where he obtained a Koshland postdoctoral fellowship. He focused on studying how proteins self-assemble into high-order structures from a physical and cellular perspective. In 2021, he obtained a Ramon y Cajal grant and he joined the Structural Biology Department of the IBMB in 2022 to start his group on protein assembly and evolution. |
Profile
| Institution | IBMB |
| Position | Ramon y Cajal Group Leader |
| Home page | https://www.linkedin.com/in/hector-garcia-seisdedos-05234455/ |
| Contact email | Hector.garcia-seisdedos@ibmb.csic.es |
| ORCID | 0000-0001-7722-2793 |
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| BCB Committee | Not a member |
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Research
Research topics
Publications 9 entries
- Mutation-induced filaments of folded proteins are inert and non-toxic in a cellular system Article · 15 Sep 2025
- Structural determinants of co-translational protein complex assembly Article · Feb 2025
- Agglomeration: when folded proteins clump together Article · Dec 2023
- Active site center redesign increases protein stability preserving catalysis in thioredoxin Article · 19 Aug 2022
- Mutant libraries reveal negative design shielding proteins from supramolecular self-assembly and relocalization in cells Article · 25 Jan 2022
View all (4 more)
- Proteins evolve on the edge of supramolecular self-assembly Article · 2 Aug 2017
- Symmetry Breaking in Homo-Oligomers: The Curious Case of Mega-Hemocyanin Article · Jan 2015
- Probing the Mutational Interplay between Primary and Promiscuous Protein Functions: A Computational-Experimental Approach Article · 14 Jun 2012
- How many ionizable groups can sit on a protein hydrophobic core? Article · 30 Sep 2011