María Salud García Gutiérrez
Translational neuropsychopharmacology of neurological and psychiatric diseases · IN
Biography
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Associate Professor (Profesora Titular) of Pharmacology at the Universidad Miguel Hernández (UMH), Department of Pharmacology, Paediatrics and Organic Chemistry, and Group Leader of the laboratory Translational neuropsychopharmacology of neurological and psychiatric diseases at the Instituto de Neurociencias de Alicante (UMH-CSIC).Her research focuses on neuropsychopharmacology, analysing how addictions, depression and stress affect the brain, and she currently combines molecular studies of ageing and cognitive decline with the aim of discovering new treatments for neuropsychiatric diseases. She has been carrying out translational neuropsychopharmacology research uninterruptedly since 2006, with expertise in animal models (stress, anxiety and depression), pharmacological studies and the processing of brain samples (human and rodent), genotyping, cryostat sections, microdissections, RNA extraction, real-time PCR and western blotting. She has collaborated in 19 research projects (including a European Twinning Project), being PI in two of them (FIS2018 and Consolidated GVA2022), and has 66 publications. Member of the national network of Addictive Disorders since 2008, currently the Primary Care Addictions Research Network. She teaches Pharmacology in the Degrees of Pharmacy, Medicine and Podiatry and in UMH master's programmes (Neurosciences and Translational Neuropsychopharmacology). Vice-Dean of Projection and Communication for the Degree in Pharmacy (Faculty of Pharmacy, UMH), Deputy Director of the Official Master's Degree in Translational Neuropsychopharmacology (2015-present) and previously Coordinator of the Degree in Pharmacy (2016-2017). Co-director of four doctoral theses. Reviewer for international journals and Guest Editor for Biomolecules, Frontiers in Psychiatry and Frontiers in Pharmacology. (Description curated from publicly available data.) |
Profile
| Institution | UMH |
| Position | Associate Professor (Profesora Titular) |
| Home page | https://www.linkedin.com/in/maria-salud-garcia-gutierrez-842893b7/ |
| Contact email | maria.ggutierrez@umh.es |
| ORCID | 0000-0001-6106-6247 |
BCB Hub
| BCB Committee | Not a member |
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Projects, networks, transfer & teaching
Teaching
Master programs
- Master in Neuroscience: from Research to the Clinic - Universidad Miguel Hernández: Neuropathology (2024-2026; subject coordinator in 2026)
- Master in Translational Neuropsychopharmacology - Universidad Miguel Hernández (Deputy Director, 2015-present): Neuroanatomical and Molecular Bases in Neuropsychopharmacology; Basic Pharmacology in the Treatment of Drug Addiction and Animal Models; Basic Pharmacology in the Treatment of Neurodegenerative Diseases and Animal Models; Basic Pharmacology in the Treatment of Psychiatric Diseases and Animal Models; Preparation of Scientific Projects and Articles; General Principles of Translational Research in Neuropsychopharmacology; Computerised Practicals in Psychopharmacology; Master's Thesis (2024-2026)
- Source: https://www.umh.es/contenido/Estudios/:persona_109981/datos_es.html
Publications 73 entries
- Dual Role of the Spinal Endocannabinoid System in Response to Noxious Stimuli: Antinociceptive Pathways and Neuropathic Pain Mechanisms Article · 3 Nov 2025
- Additive antinociceptive action of intrathecal anandamide reuptake inhibitor and morphine in the management of post-incisional pain in rats Article · Aug 2024
- Cannabinoid Analgesia in Postoperative Pain Management: From Molecular Mechanisms to Clinical Reality Article · 6 Jun 2024
- Adolescent intermittent ethanol exposure decreases perineuronal nets in the hippocampus in a sex dependent manner: Modulation through pharmacological inhibition of RPTPβ/ζ Article · Apr 2024
- Understanding the Biological Relationship between Migraine and Depression Article · 30 Jan 2024
View all (68 more)
- Molecular Changes Associated with Suicide Article · 24 Nov 2023
- Alterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents Article · Oct 2023
- Cognitive Alterations in Addictive Disorders: A Translational Approach Article · 23 Jun 2023
- Emotional Processing and Maltreatment During Childhood as Factors of Vulnerability to Alcohol Abuse in Young Adults Article · 21 Jun 2023
- Methods to Identify Cognitive Alterations from Animals to Humans: A Translational Approach Article · 21 Apr 2023
- Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model Article · 18 Apr 2023
- Role of CB2 cannabinoid receptor in the development of food addiction in male mice Article · Apr 2023
- Editorial: Cannabidiol treatment in neurotherapeutic interventions, volume II Article · 23 Feb 2023
- Role of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies Article · 25 May 2022
- Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders Article · 26 Apr 2022
- Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders Article · 15 Apr 2022
- Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice Article · 13 Apr 2022
- Biomarkers of the Endocannabinoid System in Substance Use Disorders Article · 3 Mar 2022
- Biomarkers Book / chapter · 2022
- CB2 Receptor Involvement in the Treatment of Substance Use Disorders Article · 20 Oct 2021
- Editorial: Cannabidiol Treatment in Neurotherapeutic Interventions Article · 18 Oct 2021
- Editorial: The Search for Biomarkers in Psychiatry Article · 12 Jul 2021
- Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders Article · 20 May 2021
- Differences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes? Article · Jan 2021
- Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders Article · 19 Nov 2020
- Cannabis Use in Pregnant and Breastfeeding Women: Behavioral and Neurobiological Consequences Article · 2 Nov 2020
- Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? Article · 17 Jul 2020
- Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality Article · 15 May 2020
- Endocannabinoid System Components as Potential Biomarkers in Psychiatry Article · 27 Apr 2020
- Association of cannabinoid receptor genes ( CNR1 and CNR2 ) polymorphisms and panic disorder Article · 2 Mar 2020
- Gender differences in the effects of cannabidiol on ethanol binge drinking in mice Article · 9 May 2019
- Deletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice Article · Dec 2018
- Role of the endocannabinoid system in drug addiction Article · Nov 2018
- Pharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol Article · Nov 2018
- Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress Article · 16 Oct 2018
- Cannabidiol does not display drug abuse potential in mice behavior Article · 18 Jul 2018
- Effects of cannabidiol plus naltrexone on motivation and ethanol consumption Article · Jul 2018
- Alterations in Gene and Protein Expression of Cannabinoid CB2 and GPR55 Receptors in the Dorsolateral Prefrontal Cortex of Suicide Victims Article · Jul 2018
- Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson's Disease Article · Apr 2018
- Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam Article · Nov 2017
- Psychological symptomatology and impaired prepulse inhibition of the startle reflex are associated with cannabis-induced psychosis Article · 26 Jun 2017
- The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4-Year Follow-Up Study Article · 11 May 2017
- Involvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice Article · Apr 2017
- Cannabidiol reduces ethanol consumption, motivation and relapse in mice Article · 13 Feb 2017
- Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice Article · 13 Nov 2015
- Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain Article · Oct 2015
- Evidence against a critical role of CB1 receptors in adaptation of the hypothalamic–pituitary–adrenal axis and other consequences of daily repeated stress Article · Aug 2015
- Increased vulnerability to ethanol consumption in adolescent maternal separated mice Article · 18 May 2015
- Regulatory role of the cannabinoid CB 2 receptor in stress‐induced neuroinflammation in mice Article · 15 May 2014
- Abnormal Expression Pattern of Notch Receptors, Ligands, and Downstream Effectors in the Dorsolateral Prefrontal Cortex and Amygdala of Suicidal Victims Article · 23 Oct 2013
- Synaptic plasticity alterations associated with memory impairment induced by deletion of CB2 cannabinoid receptors Article · Oct 2013
- Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims Article · Aug 2013
- Role of cannabinoid CB 2 receptor in the reinforcing actions of ethanol Article · 16 Jul 2013
- Role of CB2 Cannabinoid Receptors in the Rewarding, Reinforcing, and Physical Effects of Nicotine Article · 2 Jul 2013
- Accumbal dopamine, noradrenaline and serotonin activity after naloxone-conditioned place aversion in morphine-dependent mice Article · Aug 2012
- Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice Article · 5 Jul 2012
- Voluntary Alcohol Drinking Enhances Proopiomelanocortin Gene Expression in Nucleus Accumbens Shell and Hypothalamus of S ardinian Alcohol‐Preferring Rats Article · 22 Jun 2012
- Decreased Cocaine Motor Sensitization and Self-Administration in Mice Overexpressing Cannabinoid CB2 Receptors Article · 14 Mar 2012
- Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels Article · Mar 2012
- Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine Article · Feb 2012
- Chronic blockade of cannabinoid CB 2 receptors induces anxiolytic‐like actions associated with alterations in GABA A receptors Article · 25 Jan 2012
- Cannabinoid Type 2 Receptor Activation Downregulates Stroke-Induced Classic and Alternative Brain Macrophage/Microglial Activation Concomitant to Neuroprotection Article · Jan 2012
- Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors Article · Apr 2011
- Deletion of CB2 Cannabinoid Receptor Induces Schizophrenia-Related Behaviors in Mice Article · 23 Mar 2011
- Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol‐preferring sP rats Article · 11 Feb 2011
- Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects Article · 2011
- Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice Article · 13 Sep 2010
- Regulation of Fas receptor/Fas‐asssociated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain Article · 19 May 2010
- Depression‐resistant endophenotype in mice overexpressing cannabinoid CB 2 receptors Article · 26 Apr 2010
- Decreased GABA A and GABA B receptor functional activity in cannabinoid CB 1 receptor knockout mice Article · 8 Feb 2010
- CB1 Receptor Blockade Decreases Ethanol Intake and Associated Neurochemical Changes in Fawn‐Hooded Rats Article · 17 Dec 2009
- The cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines Article · 13 Oct 2009
- Métodos de evaluación de trastornos cognitivos en modelos animales Article · 2008
