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Tool

GEARS

GEARS (Global parameter Estimation with Automated Regularisation via Sampling) is a MATLAB toolbox for parameter estimation in nonlinear dynamic (ODE) models. It combines global optimisation, reduction of the parameter search space and regularised estimation to avoid both underfitting and overfitting with little user supervision.

Basic Information

Repository https://github.com/JaPitt/GEARS
Documentation https://japitt.github.io/GEARS/
Main publication (DOI) 10.5281/zenodo.1420465 view
Contact email jp00191.su@gmail.com
Authors/Maintainers Julio Rodriguez Banga
Type of application Desktop application
Programming languages MATLAB
Keywords Biosystems Modeling, Dynamical systems, Mathematical optimization

Technical details

Input file formats
Output file formats
Software compatibility Linux, Windows
Hardware requirements
Type of containerization
Wrapper type
Compatible tools
Funding resource
Funding support
Statistics
Unique users (last 12 months)
Unique users (since first release)
Software downloads (last 12 months)
Software downloads (since first release)
Jobs submitted (last 12 months)
Jobs submitted (since first release)
Repository clones (last 12 months)
Repository clones (since first release)
Citations (last 12 months) <100 (~0 as of 15/10/2026)
Citations (since first release) <100 (0 as of 15/10/2026)
Early-stage researcher effort (development)
Early-stage researcher effort (maintenance)
Technician-supported effort (development)
Technician-supported effort (maintenance)
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Total effort (development)
Total effort (maintenance)

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