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Tool

VAIRO

Provides ways to inform AlphaFold predictions with additional and selected prior knowledge, through site-specific variants, predefined alignments and templates. It allows rescuing weaker interactions to complete the view of molecular assemblies, and reveals otherwise inaccessible dynamic states. Command-line program (vairo) and graphical interface (VAIROGUI).

Basic Information

Repository https://github.com/arcimboldo-team/vairo
Documentation http://chango.ibmb.csic.es/vairo.html
Main publication (DOI) 10.1002/pro.70481 view
Contact email massimo.sammito@gmail.com
Authors/Maintainers Isabel Uson Finkenzeller
Type of application Command line pipeline, Desktop application
Programming languages Python
Keywords Structural bioinformatics, Molecular flexibility, Structure prediction, Protein-Protein Interactions

Technical details

Input file formats
Output file formats
Software compatibility
Hardware requirements
Type of containerization Conda
Wrapper type
Compatible tools
Funding resource
Funding support
Statistics
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Software downloads (last 12 months)
Software downloads (since first release)
Jobs submitted (last 12 months)
Jobs submitted (since first release)
Repository clones (last 12 months)
Repository clones (since first release)
Citations (last 12 months) <100 (~0 as of 15/10/2026)
Citations (since first release) <100 (0 as of 15/10/2026)
Early-stage researcher effort (development)
Early-stage researcher effort (maintenance)
Technician-supported effort (development)
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Total effort (maintenance)

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