Detalle de: A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection
| Title | A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection |
| Abstract |
One of the current greatest challenges of Chagas disease is the establishment of biomarkers to assess the efficacy of drugs in a short period of time. In this context, the reactivity of sera from 66 adults with chronic indeterminate Chagas disease (IND) for a set of four Trypanosoma cruzi antigens (KMP11, PFR2, HSP70, and 3973 d ) was analyzed before and after benznidazole treatment. |
| Apa Reference | Egui, A., Thomas, M. C., Fernández-Villegas, A., Pérez-Antón, E., Gómez, I., Carrilero, B., del Pozo, Á., Ceballos, M., Andrés-León, E., López-Ruz, M. Á., Gainza, E., Oquiñena, E., Segovia, M., & López, M. C. (2019). A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection. Antimicrobial Agents and Chemotherapy, 63(10). 10.1128/aac.02436-18 |
| Doi | 10.1128/AAC.02436-18 |
| Publication Date | Oct 2019 |
| Publication Type | Article |
| Researcher | Eduardo Andrés-León |
| Ontology | |
| Research Groups | Computational Biomedicine and Health Data Science |
| Tools |