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Researcher

Eduardo Andrés-León

Computational Biomedicine and Health Data Science · IPBLN

Biography

I completed a degree and a PhD in Biological Sciences at the Universidad Autónoma de Madrid. I began my research career in the field of bioinformatics under the mentoring of Prof. Alfonso Valencia (H index 108, >67,000 citations), working at the Spanish National Centre for Biotechnology (CNB), the Spanish National Bioinformatics Institute (ISCIII-INB), and the Spanish National Cancer Research Centre (CNIO). In 2013, I joined the Institute of Biomedicine of Seville (IBIS) as head of the Bioinformatics Unit within the Computational Biology Group led by Dr. Ana M. Rojas (H index 31, >2,900 citations). Since 2015, I have been based at the Institute of Parasitology and Biomedicine “López-Neyra” (IPBLN), collaborating closely with Dr. Javier Martín (H index 79, >32,000 citations).

In March 2025, I was appointed as a Tenured Scientist (Científico Titular) at the Spanish National Research Council (CSIC), in the specialty of “Applications of Artificial Intelligence in Life Sciences.” Over the past years, I have broadened my expertise into the areas of machine learning (ML), natural language processing (NLP), and deep learning, applying these approaches to complex biomedical data. Currently, I lead projects focused on the identification of biomarkers for complex diseases using ML methods, as well as the application of computer vision and deep learning for the analysis of medical images. These efforts support personalized medicine by facilitating diagnosis and treatment selection.

My research career has also included the development of computational tools to explore non-coding genetic regulators in human disease. Notably, I have studied miRNA–mRNA interactions across multiple cancer types, linking them to patient survival, and extended this work to autoimmune, infectious, and neurological diseases.

With over 70 scientific publications, I actively collaborate with numerous research groups, contributing to over 40 national and international research projects. I have supervised seven Master’s theses and frequently present at scientific conferences—receiving a best poster award—and contribute as a lecturer in Master’s programs, specialization diplomas, and summer courses at various Spanish universities and CSIC training initiatives.

In addition to my research activities, I serve on the editorial board of a scientific journal, participate in organizing international symposiums, and regularly act as a reviewer for more than 30 journals (conducting ~35 reviews annually). I have also been a member of evaluation panels, including the Innova call from the Spanish Association for Cancer Research, focused on transferring research findings into clinical applications.

I am also part of the IPBLN’s scientific dissemination unit, participating in outreach initiatives such as the European Researchers’ Night, student visits, and media engagement to communicate scientific findings to the public.

With 20 years of experience in bioinformatics, I have developed independent and collaborative research lines in high-level institutions, working on large-scale projects with cutting-edge technologies, including single-cell “omics” for studying SARS-CoV-2. I remain deeply committed to scientific dissemination and translational research that bridges computational biology and biomedical innovation.

Profile

Institution IPBLN
Position Tenured Scientist (Científico Titular), Head of the Bioinformatics Unit
Home page http://bioinfo.ipb.csic.es
Contact email eduardo.andres@csic.es
ORCID 0000-0002-0621-9914

Research

Research topics

OmicsComputational MethodsResourcesTranscriptomicsRNA Sequencing (RNA-seq)Data AnalysisArtificial IntelligenceMachine Learning in BiologyBioinformatics Software and ToolsAnalysis packages (R, Python, etc.)Data VisualizationApplications of Computational Biology
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Model organismsGenomicsFunctional genomicsBioinformatics InfrastructureBiological DatabasesExpression ProfilingComputational TechniquesHigh-performance ComputingParallel ComputingPersonal medicineVariant callingEpigenomicsDNA methylation3D chromatin structureContainers ComputingStatistical Methods for BiologyWeb-serviceWorkflow managersSequence analysisSequence AlignmentExperimental designMappingPathway analysisMultivariate statisticsSingle-cell omicsSingle-cell (scRNA-seq)MetagenomicsCloud ComputingClinical dataSpatial transcriptomics

Research lines

Projects, networks, transfer & teaching

Teaching

Master programs

Funded projects 2

Publications 101 entries

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