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Orcid Publication

Detalle de: Novel Use of a Genetic Algorithm for Protein Structure Prediction: Searching Template and Sequence Alignment Space

Title Novel Use of a Genetic Algorithm for Protein Structure Prediction: Searching Template and Sequence Alignment Space
Abstract

A novel genetic algorithm was applied to all CASP5 targets. The algorithm simultaneously searches template and alignment space. Results show that the current implementation of the method is perhaps most useful in recognizing and refining remote homology targets. This new method is briefly described and results are analyzed. Strengths and weaknesses of the current implementation of the algorithm are discussed.

Apa Reference Contreras-Moreira, B., Fitzjohn, P. W., Offman, M., Smith, G. R., & Bates, P. A. (2003). Novel use of a genetic algorithm for protein structure prediction: Searching template and sequence alignment space. Proteins: Structure, Function, and Genetics, 53(S6), 424–429. 10.1002/prot.10549
Doi 10.1002/prot.10549
Publication Date 2003
Publication Type Article
Researcher Bruno Contreras Moreira
Ontology Sequence Alignment, Structure prediction
Research Groups Computational and structural biology @EEAD-CSIC
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