Detalle de: Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2
| Title | Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2 |
| Abstract |
We observed repeated, independent emergence of mutations in the SARS-CoV-2 spike involving amino acids 1163 and 1167, within the HR2 functional motif. Conclusions derived from evolutionary and genomic diversity analysis suggest that the co-occurrence of both mutations might pose an advantage for the virus and therefore a threat to effective control of the epidemic. |
| Apa Reference | Ruiz-Rodriguez, P., Francés-Gómez, C., Chiner-Oms, Á., López, M. G., Jiménez-Serrano, S., Cancino-Muñoz, I., Ruiz-Hueso, P., Torres-Puente, M., Bracho, M. A., D’Auria, G., Martinez-Priego, L., Guerreiro, M., Montero-Alonso, M., Gómez, M. D., Piñana, J. L., González-Candelas, F., Comas, I., Marina, A., … Coscolla, M. (2021). Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2. MBio, 12(6). 10.1128/mbio.02315-21 |
| Doi | 10.1128/mBio.02315-21 |
| Publication Date | 21 Dec 2021 |
| Publication Type | Article |
| Researcher | Paula Ruiz Rodríguez |
| Ontology | Genomics, Sequence analysis |
| Research Groups | PathoGenOmics |
| Tools |