Detalle de: Finding common regions of alteration in copy number data
| Title | Finding common regions of alteration in copy number data |
| Abstract |
In this chapter, we review some recent methods designed for detecting recurrent copy number regions, that is, genomic regions that show evidence of being altered in a set of samples. We analyze Affymetrix SNP6 data from 87 Her2-type breast tumors from a recent study using three different methods, showing different definitions and features of common regions: studying heterogeneity in copy number profiles, refining candidates for driver oncogenes, and consolidating broad amplifications. |
| Apa Reference | Rueda, O. M., Diaz-Uriarte, R., & Caldas, C. (2013). Finding Common Regions of Alteration in Copy Number Data. Array Comparative Genomic Hybridization, 339–353. 10.1007/978-1-62703-281-0_21 |
| Doi | 10.1007/978-1-62703-281-0_21 |
| Publication Date | 2013 |
| Publication Type | Book / chapter |
| Researcher | Ramon Díaz Uriarte |
| Ontology | Genomics |
| Research Groups | Bioinformatics and Computational Biology in Cancer Evolution |
| Tools |