Research Group

Detalle de: Bioinformatics and Computational Biology in Cancer Evolution

Title	Bioinformatics and Computational Biology in Cancer Evolution
Description	Bioinformatics and computational biology: development and implementation of methods for the analysis of high-throughput data, mainly in evolutionary biology of cancer
Home Page	https://www.csic.es/en/investigation/research-at-csic/research-groups/bioinformatics-and-computational-biology-cancer-evolution
Contact Email	r.diaz@uam.es
Collaborating Companies
Spin Off
Patents
Hpc Resources
Institution	IIBM
Ontology	Omics, Computational Methods, Resources, Transcriptomics, RNA Sequencing (RNA-seq), Data Analysis, Artificial Intelligence, Machine Learning in Biology, Bioinformatics Software and Tools, Analysis packages (R, Python, etc.), Applications of Computational Biology, Bioinformatics enabling techniques, Benchmarking, Large language models, Computational models and simulations, Computational Techniques, High-performance Computing, Parallel Computing, Containers Computing, Statistical Methods for Biology, Web-service, Molecular evolution, Evolutionary modelling, Sequence analysis, Sequence Alignment, Phylogenetic Analysis, Mapping, Deep Learning in Biology, Clinical data
Tools	Pomelo2, Tnasas, SignS, GeneSrF, EvAM-Tools
Service Units
Research Lines	Computational methods for cancer evolution
Funded Projects
Selected Publications	Adaptive therapy in cancer: the role of restrictions in the accumulation of mutations Preprint · 22 May 2023 Global epistasis on fitness landscapes Article · 3 Apr 2023 The long and winding road to understanding organismal construction Article · Sep 2022 Ten quick tips for biomarker discovery and validation analyses using machine learning Article · 11 Aug 2022 Simulating Evolution in Asexual Populations with Epistasis Book / chapter · 2021 View all (52 more) Estimating the predictability of cancer evolution Article · Jul 2019 OncoSimulR: genetic simulation with arbitrary epistasis and mutator genes in asexual populations Article · 10 Feb 2017 OncoSimulR: genetic simulation of cancer progression with arbitrary epistasis and mutator genes Preprint · 14 Aug 2016 Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21 Article · 10 Nov 2014 Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis Article · 23 Apr 2014 ADaCGH2: parallelized analysis of (big) CNA data Article · 14 Feb 2014 Correction: An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility Article · 21 Oct 2013 An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility Article · 23 Sep 2013 A Bayesian HMM with random effects and an unknown number of states for DNA copy number analysis Article · Jan 2013 Finding common regions of alteration in copy number data Book / chapter · 2013 An optimized predictor panel for colorectal cancer diagnosis based on the combination of tumor-associated antigens obtained from protein and phage microarrays Article · Aug 2012 miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy Article · 28 Jul 2011 CNVassoc: Association analysis of CNV data using R Article · 24 May 2011 Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays Article · Mar 2011 Functionally opposing effects of testosterone on two different types of parasite: implications for the immunocompetence handicap hypothesis Article · 28 Sep 2010 waviCGH: a web application for the analysis and visualization of genomic copy number alterations Article · 27 May 2010 Genomic copy number alterations in cancer: high-resolution analysis of the NCI-60 panel Article · Apr 2010 Abstract 1685: Identification of PDGFR-a as a predictive biomarker for response to Zalypsis(R) Article · Apr 2010 Identification of Tumor-associated Autoantigens for the Diagnosis of Colorectal Cancer in Serum Using High Density Protein Microarrays Article · Oct 2009 Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously Article · 23 Sep 2009 Pomelo II: finding differentially expressed genes Software · 12 May 2009 RJaCGH: Bayesian analysis of aCGH arrays for detecting copy number changes and recurrent regions Article · 6 May 2009 Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells Article · 10 Apr 2009 Mecp2-Null Mice Provide New Neuronal Targets for Rett Syndrome Article · 7 Nov 2008 PaLS: filtering common literature, biological terms and pathway information Article · 19 May 2008 SignS: a parallelized, open-source, freely available, web-based tool for gene selection and molecular signatures for survival and censored data Software · 21 Jan 2008 A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array", BMC Bioinformatics 2007, 8: 145 Article · 16 Oct 2007 Genomic Profiling of Circulating Plasma RNA for the Analysis of Cancer Article · 1 Oct 2007 GeneSrF and varSelRF: a web-based tool and R package for gene selection and classification using random forest Software · 3 Sep 2007 ADaCGH: A Parallelized Web-Based Application and R Package for the Analysis of aCGH Data Article · 15 Aug 2007 Molecular heterogeneity in chronic lymphocytic leukemia is dependent on BCR signaling: clinical correlation Article · 5 Jul 2007 Flexible and Accurate Detection of Genomic Copy-Number Changes from aCGH Article · 22 Jun 2007 Asterias: integrated analysis of expression and aCGH data using an open-source, web-based, parallelized software suite Software · 8 May 2007 Levels of p27kip1 determine Aplidin sensitivity Article · 1 Apr 2007 GEPAS, an experiment-oriented pipeline for the analysis of microarray gene expression data Article · 1 Jul 2005 Discovering molecular functions significantly related to phenotypes by combining gene expression data and biological information Article · 19 Apr 2005 Supervised Methods with Genomic Data: a Review and Cautionary View Other · 24 Mar 2005 Gene expression analysis of chromosomal regions with gain or loss of genetic material detected by comparative genomic hybridization Article · 20 Sep 2004 Expression Profiling of T-Cell Lymphomas Differentiates Peripheral and Lymphoblastic Lymphomas and Defines Survival Related Genes Article · 1 Aug 2004 DNMAD: web-based diagnosis and normalization for microarray data Article · 9 Jul 2004 New challenges in gene expression data analysis and the extended GEPAS Article · 1 Jul 2004 FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes Article · 22 Jan 2004 The Use of Go Terms to Understand the Biological Significance of Microarray Differential Gene Expression Data Book / chapter · 2004 Molecular Signatures from Gene Expression Data Preprint · 2004 Gene expression data preprocessing Article · 22 Mar 2003 An Approach to Inferring Transcriptional Regulation Among Genes From Large-Scale Expression Data Article · Feb 2003 Using gene ontology on genome-scale studies to find significant associations of biologically relevant terms to groups of genes Conference paper · 2003 Territorial intrusion risk and antipredator behaviour: a mathematical model Article · 7 Jun 2001 Covariation of Life-History Traits in Lacertid Lizards: A Comparative Study Article · Jan 1997 Reconstructing Ancestral Trait Values Using Squared-Change Parsimony Book / chapter · 1997 Influence of Behavioral Thermoregulation on the Use of Vertical Surfaces by Iberian Wall Lizards Podarcis hispanica Article · Dec 1996 Testing Hypotheses of Correlated Evolution Using Phylogenetically Independent Contrasts: Sensitivity to Deviations from Brownian Motion Article · 1 Mar 1996
Researchers	Ramon Díaz Uriarte

Suggest changes

← Return to Home