Detalle de: TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage
| Title | TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage |
| Abstract |
Key Points TAILS proteomics identified 2938 human platelet proteins, pervasive proteolytic processing, and precise proteolytic cleavage sites in stored platelets. During storage, metalloproteinases were predominantly involved in proteolytic processing, while other proteinases were mainly involved in degradation. |
| Apa Reference | Prudova, A., Serrano, K., Eckhard, U., Fortelny, N., Devine, D. V., & Overall, C. M. (2014). TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage. Blood, 124(26), e49–e60. 10.1182/blood-2014-04-569640 |
| Doi | 10.1182/blood-2014-04-569640 |
| Publication Date | 18 Dec 2014 |
| Publication Type | Article |
| Researcher | Ulrich Eckhard |
| Ontology | Proteomics |
| Research Groups | Synthetic Structural Biology |
| Tools |