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Detalle de: Azepane Quaternary Amino Acids As Effective Inducers of 3 10 Helix Conformations

Title Azepane Quaternary Amino Acids As Effective Inducers of 3 10 Helix Conformations
Abstract

A simple method for the synthesis of an azepane quaternary amino acid in enantiopure form is described. Theoretical, NMR, and X-ray studies indicated that this azepane-derived amino acid is an effective stabilizer of 3(10) helical structures in short peptides.

Apa Reference Núñez-Villanueva, D., Infantes, L., García-López, M.T., González-Muñiz, R. & Martín-Martínez, M. (2012). Azepane Quaternary Amino Acids As Effective Inducers of 3 10 Helix Conformations. The Journal of Organic Chemistry, 77(21), 9833-9839. 10.1021/jo301379r
Doi 10.1021/jo301379r
Publication Date 22 Oct 2012
Publication Type Article
Researcher Mercedes Martín Martínez
Ontology
Research Groups
Tools

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