Detalle de: The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
| Title | The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity |
| Abstract |
The influence of several modifications on the GPE tripeptide structure upon the binding to GluRs and on their neuroprotective effects has been studied. The results indicated that the prevention of neuronal death showed by GPE and some analogues is not directly related to their affinity at glutamate receptors. |
| Apa Reference | Alonso De Diego, S.A., Gutiérrez-Rodríguez, M., Pérez de Vega, M.J., González-Muñiz, R., Herranz, R., Martín-Martínez, M., Cenarruzabeitia, E., Frechilla, D., Río, J.D., Jimeno, M.L. & García-López, M.T. (2006). The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity. Bioorganic & Medicinal Chemistry Letters, 16(13), 3396-3400. 10.1016/j.bmcl.2006.04.033 |
| Doi | 10.1016/j.bmcl.2006.04.033 |
| Publication Date | Jul 2006 |
| Publication Type | Article |
| Researcher | Mercedes Martín Martínez |
| Ontology | Molecular Interactions/Docking |
| Research Groups | |
| Tools |