Detalle de: DREIMT: a drug repositioning database and prioritization tool for immunomodulation
| Title | DREIMT: a drug repositioning database and prioritization tool for immunomodulation |
| Abstract |
Motivation Drug immunomodulation modifies the response of the immune system and can be therapeutically exploited in pathologies such as cancer and autoimmune diseases. Results DREIMT is a new hypothesis-generation web tool which performs drug prioritization analysis for immunomodulation. DREIMT provides significant immunomodulatory drugs targeting up to 70 immune cells subtypes through a curated database that integrates 4,960 drug profiles and ~2,6K immune gene expression signatures. The tool also suggests potential immunomodulatory drugs targeting user-supplied gene expression signatures. Final output includes drug-signature association scores, FDRs and downloadable plots and results tables. Availability http://www.dreimt.org Contact falshahrour@cnio.es ; ggomez@cnio.es |
| Apa Reference | Troulé, K., López-Fernández, H., García-Martín, S., Reboiro-Jato, M., Carretero-Puche, C., Martorell-Marugán, J., Martín-Serrano, G., Carmona-Sáez, P., González-Peña, D., Al-Shahrour, F. & Gómez-López, G. (2020). DREIMT: a drug repositioning database and prioritization tool for immunomodulation. 10.1101/2020.06.24.168468 |
| Doi | 10.1101/2020.06.24.168468 |
| Publication Date | 24 Jun 2020 |
| Publication Type | Preprint |
| Researcher | Pedro Carmona-Saez |
| Ontology | Transcriptomics, Biological Databases, Expression Profiling, Web-service, Drug Discovery and design |
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| Tools |