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Detalle de: Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique

Title Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique
Abstract

Multidrug-resistant(MDR) tuberculosis in Southern Africa is of great concern, exacerbated by the spread of a clone harboring a mutation missed by Xpert Ultra. In Southern Mozambique, the presence of such mutation and rising cases of non-MDR isoniazid resistance highlights the need to ensure accurate detection of antimicrobial-resistance in the country.

Apa Reference Mariner-Llicer, C., Saavedra Cervera, B., Mambuque, E., Gomes, N., Munguambe, S., Villamayor, L., Cancino-Muñoz, I., Torres-Puente, M., Nguenha, D., Respeito, D., Tembe, G., López, M.G., Comas, I. & García-Basteiro, A.L. (2023). Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique. Clinical Infectious Diseases, 78(4), 842-845. 10.1093/cid/ciad684
Doi 10.1093/cid/ciad684
Publication Date 4 Dec 2023
Publication Type Article
Researcher Iñaki Comas Espadas
Ontology Mutation Analysis and design, Drug resistance
Research Groups
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