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Detalle de: Proper Assignation of Reactivation in a COVID-19 Recurrence Initially Interpreted as a Reinfection

Title Proper Assignation of Reactivation in a COVID-19 Recurrence Initially Interpreted as a Reinfection
Abstract

A 77-year-old man (case R) with previous diagnosis of a mild COVID-19 episode was hospitalized 35 days later. On day 23 postadmission, he developed a second COVID-19 episode, now severe, and finally died. Initially, case R’s COVID-19 recurrence was interpreted as a reinfection due to the exposure to a SARS-CoV-2 RT-PCR–positive roommate. However, whole-genome sequencing indicated that case R’s recurrence corresponded to a reactivation of the strain involved in his first episode. Case R’s reactivation had major consequences, leading to a more severe episode, and causing subsequent transmission to another 2 hospitalized patients, 1 of them with fatal outcome.

Apa Reference Pérez-Lago, L., Martínez-Lozano, H., Pajares Díaz, J.A., Díaz Gómez, A., Machado, M., Sola-Campoy, P.J., Herranz, M., Buenestado-Serrano, S., Valerio, M., Olmedo, M., Andrés Zayas, C., Comas, I., González Candelas, F., Bañares, R., Catalán, P., Muñoz, P. & García de Viedma, D. (2021). Proper Assignation of Reactivation in a COVID-19 Recurrence Initially Interpreted as a Reinfection. The Journal of Infectious Diseases, 224(5), 788-792. 10.1093/infdis/jiab302
Doi 10.1093/infdis/jiab302
Publication Date 9 Jun 2021
Publication Type Article
Researcher Iñaki Comas Espadas
Ontology Genome Sequencing
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