Detalle de: Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches
| Title | Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches |
| Abstract |
Pathogenic and opportunistic free-living amoebae such as Acanthamoeba spp. can cause keratitis ( Acanthamoeba keratitis [AK]), which may ultimately lead to permanent visual impairment or blindness. Acanthamoeba can also cause rare but usually fatal granulomatous amoebic encephalitis (GAE). Current therapeutic options for AK require a lengthy treatment with nonspecific drugs that are often associated with adverse effects. |
| Apa Reference | Sebastián-Pérez, V., Sifaoui, I., Reyes-Batlle, M., Domínguez-De Barros, A., López-Arencibia, A., Campillo, N.E., Piñero, J.E., Lorenzo-Morales, J. & Gil, C. (2021). Discovery of Amoebicidal Compounds by Combining Computational and Experimental Approaches. Antimicrobial Agents and Chemotherapy, 65(2). 10.1128/AAC.01749-20 |
| Doi | 10.1128/AAC.01749-20 |
| Publication Date | 20 Jan 2021 |
| Publication Type | Article |
| Researcher | Carmen Gil |
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