Detalle de: S N 2 vs. E2 on quaternary centres: an application to the synthesis of enantiopure β 2,2 -amino acids
| Title | S N 2 vs. E2 on quaternary centres: an application to the synthesis of enantiopure β 2,2 -amino acids |
| Abstract |
S(N)2 and E2 competing reactions in cyclic sulfamidates can be modulated by the change of an amide group to an ester group attached to the quaternary carbon activated for the nucleophilic attack, allowing an easy approach to enantiopure alpha,alpha-disubstituted beta-amino acids. |
| Apa Reference | Avenoza, A., Busto, J.H., Corzana, F., Jiménez-Osés, G. & Peregrina, J.M. (2004). S N 2 vs. E2 on quaternary centres: an application to the synthesis of enantiopure β 2,2 -amino acids. Chem. Commun.(8), 980-981. 10.1039/b400282b |
| Doi | 10.1039/b400282b |
| Publication Date | 2004 |
| Publication Type | Article |
| Researcher | Gonzalo Jiménez-Osés |
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