Gonzalo Jiménez-Osés
Computational Chemistry · CICBIOGUNE
Biography
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Gonzalo Jiménez-Osés is an Ikerbasque Research Professor and Principal Investigator at CIC bioGUNE since 2019, where he leads the Computational Chemistry Group (CCG), and Co-Founder and Chief Scientific Officer of Protellix since 2026. The Computational Chemistry Group (CCG) at CIC bioGUNE aims to create a solid platform for the theoretical prediction of chemical reactions for bioconjugation, designing and simulation of therapeutic peptides and proteins, and understanding Glycochemistry processes. A strong emphasis is also made on the Computer-Aided Enzyme Engineering and Directed Evolution. Before that, he was a Ramón y Cajal Investigator at the Universidad de La Rioja (2015-2018), a Postdoctoral Scholar in the Houk group at the University of California, Los Angeles (2010-2015), and a Lecturer in Chemistry and Organic Chemistry at the Universidad de Zaragoza (2007-2010). (Description curated from publicly available data.) |
Profile
| Institution | CICBIOGUNE |
| Position | Ikerbasque Research Professor and Principal Investigator, CIC bioGUNE |
| Home page | http://www.gonzalojimenezoses.com |
| Contact email | gjoses@cicbiogune.es |
| ORCID | 0000-0003-0105-4337 |
BCB Hub
| BCB Committee | Not a member |
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Research
Research topics
Applications of Computational BiologyStructural bioinformaticsComputational models and simulationsBiomolecular simulationStructure-function relationshipDrug Discovery and designStructure predictionMolecular Interactions/DockingProtein/Nucleic Acid design
Research lines
None
Projects, networks, transfer & teaching
Industry & knowledge transfer
Spin-offs
- Protellix (co-founder and Chief Scientific Officer, since September 2026)
Teaching
Master programs
- Master in Chemistry & Biotechnology - University of La Rioja
- Master in Chemical Research - University of Zaragoza
Publications 177 entries
- Radical Enhanced Phosphorescence From Perylene‐Trityl Dyad in Solution at Room Temperature Article · 17 Sep 2026
- Density Functional Theory Charge Delocalization Error Determines Computed Activation Barriers in Enzymatic Kemp Elimination Article · 24 Jul 2026
- Rational Design of Small-Molecule Stabilizers of Human Fumarylacetoacetate Hydrolase for the Treatment of Tyrosinemia Type I Article · 12 May 2026
- Dissecting Tin-Based Activation and Anomerization Pathways in Carbohydrate Chemistry Article · 20 Jan 2026
- Controlled Self-Immolative Release of β-Lapachone via an Optimized para -Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy Article · 15 Dec 2025
View all (172 more)
- Photocatalytic Minisci Approach to Chiral 2-Hetaryl-1,2-aminoalcohols from β-Hydroxy-α-amino Acid-Derived Redox Active Esters Article · 5 Nov 2025
- Cover Image, Volume 15, Issue 5 Article · Sep 2025
- Computation of Protein Thermostability and Epistasis Article · Sep 2025
- Electrostatic atlas of non-covalent interactions built into metal–organic frameworks Article · 27 Aug 2025
- Structure Prediction of Alternate Frame Folding Systems with AlphaFold3 Article · 27 Jul 2025
- Organic Carbon Monoxide Prodrugs Activated by Endogenous Reactive Oxygen Species for Targeted Delivery Article · 3 Jul 2025
- The disease‐linked R336C mutation in cystathionine β‐synthase disrupts communication with the PLP cofactor, yet maintains the enzyme's overall structural integrity Article · 6 May 2025
- Bis-CF 3 -bipyridine Ligands for the Iridium-Catalyzed Borylation of N -Methylamides Article · 16 Apr 2025
- Host–Guest Dynamic Behavior of Melatonin Encapsulated in β-Cyclodextrin Nanosponges Article · 28 Jan 2025
- Doublet Spin State Mediated Photoluminescence Upconversion in Organic Radical Donor-Triplet Acceptor Dyads Article · 19 Dec 2024
- Mechanistic Insights into Chloride‐Dependent Uncaging Reaction of Propargyl and Allene‐Protected Substrates by Pd‐Complexes Article · 10 Dec 2024
- AlphaFold2 Predicts Alternative Conformation Populations in Green Fluorescent Protein Variants Article · 3 Sep 2024
- Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution Article · 8 Aug 2024
- Different roles of the heterodimer architecture of galectin-4 in selective recognition of oligosaccharides and lipopolysaccharides having ABH antigens Article · Aug 2024
- Interplay Between Substrate Polarity and Protein Dynamics in Evolved Kemp Eliminases Article · 5 Jun 2024
- Interplay of chloride levels and palladium( ii )-catalyzed O -deallenylation bioorthogonal uncaging reactions Article · 2024
- Benzylic Radical Stabilization Permits Ether Formation During Darobactin Biosynthesis Preprint · 30 Nov 2023
- Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes Article · 10 Oct 2023
- Merging the Isonitrile‐Tetrazine (4+1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process Article · 20 Sep 2023
- Unraveling the Photophysical Characteristics, Aromaticity, and Stability of π–Extended Acene‐Quinodimethyl Thioamides† Article · 19 Sep 2023
- Thermodynamic Stabilization of Human Frataxin Preprint · 12 Sep 2023
- The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis Article · 31 Aug 2023
- Molecular Recognition of Glycan-Bearing Glycomacromolecules Presented at Membrane Surfaces by Lectins: An NMR View Article · 3 May 2023
- Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C–C Bond Cleavage Reactions Article · 3 May 2023
- Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening Article · 27 Feb 2023
- Iridium‐Catalyzed ortho ‐Selective Borylation of Aromatic Amides Enabled by 5‐Trifluoromethylated Bipyridine Ligands Article · 24 Jan 2023
- Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles Article · 17 Jan 2023
- Protoglobin‐Catalyzed Formation of cis ‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer Article · 19 Dec 2022
- NMR Investigation of Protein‐Carbohydrate Interactions: The Recognition of Glycans by Galectins Engineered with Fluorotryptophan Residues Article · 12 Dec 2022
- Regioselective Synthesis and Molecular Docking Studies of 1,5-Disubstituted 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases Article · 2 Dec 2022
- Studies on the Regioselective Rearrangement of Azanorbornanic Aminyl Radicals into 2,8-Diazabicyclo[3.2.1]oct-2-ene Systems Article · 1 Dec 2022
- Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine Article · 30 Sep 2022
- Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition by LSECtin Article · 20 Sep 2022
- Stereoselective α-Deuteration of Serine, Cysteine, Selenocysteine, and 2,3-Diaminopropanoic Acid Derivatives Article · 9 Sep 2022
- Immobilization and Stabilization of an Engineered Acyltransferase for the Continuous Biosynthesis of Simvastatin in Packed-Bed Reactors Article · 19 Jul 2022
- Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination Article · 27 Jun 2022
- Synthesis of β 2,2 -Amino Acids by Stereoselective Alkylation of Isoserine Derivatives Followed by Nucleophilic Ring Opening of Quaternary Sulfamidates Article · 22 Jun 2022
- Platform for Orthogonal N -Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents Article · 5 Jun 2022
- Synthesis and Photophysics of Phenylene Based Triplet Donor–Acceptor Dyads: ortho vs. para Positional Effect on Intramolecular Triplet Energy Transfer Article · Jun 2022
- Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods Article · 15 Apr 2022
- Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry Article · 16 Mar 2022
- A Computational Perspective on Molecular Recognition by Galectins Article · Feb 2022
- Deconvoluting the Directed Evolution Pathway of Engineered Acyltransferase LovD Article · 10 Jan 2022
- Unveiling the role of pyrylium frameworks on π-stacking interactions: a combined ab initio and experimental study Article · 2022
- Triplet photodynamic and up-conversion luminescence in donor–acceptor dyads with slip-stacked vs. co-facial arrangement Article · 2022
- Substrate Sequence Controls Regioselectivity of Lanthionine Formation by ProcM Article · 1 Nov 2021
- Computer Prediction of p K a Values in Small Molecules and Proteins Article · 10 Sep 2021
- Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions Article · 15 Jul 2021
- Cosolute modulation of protein oligomerization reactions in the homeostatic timescale Article · May 2021
- Origin and Control of Chemoselectivity in Cytochrome c Catalyzed Carbene Transfer into Si–H and N–H bonds Article · 28 Apr 2021
- Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations Article · 21 Apr 2021
- Enthalpy–Entropy Compensation in Biomolecular Recognition: A Computational Perspective Article · 20 Apr 2021
- Replacing the Rhamnose‐Xylose Moiety of QS‐21 with Simpler Terminal Disaccharide Units Attenuates Adjuvant Activity in Truncated Saponin Variants Article · 4 Feb 2021
- Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold Article · 1 Feb 2021
- Identification of Isomeric N ‐Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry Article · 14 Jan 2021
- Structural insight into the unique conformation of cystathionine β-synthase from Toxoplasma gondii Article · Jan 2021
- The two domains of human galectin-8 bind sialyl- and fucose-containing oligosaccharides in an independent manner. A 3D view by using NMR Article · 2021
- Nucleophilic catalysis of p -substituted aniline derivatives in acylhydrazone formation and exchange Article · 2021
- Biotin-phenosafranin as a new photosensitive conjugate for targeted therapy and imaging Article · 2021
- Bacteriophage PRD1 as a nanoscaffold for drug loading Article · 2021
- Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se -Michael Additions to Chiral Dehydroalanines Article · 29 Dec 2020
- A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance Article · 18 Dec 2020
- Sequential dual site-selective protein labelling enabled by lysine modification Article · Nov 2020
- Unravelling the Time Scale of Conformational Plasticity and Allostery in Glycan Recognition by Human Galectin‐1 Article · 29 Oct 2020
- Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human Lectins Article · 22 Oct 2020
- Dissecting the Essential Role of Anomeric β-Triflates in Glycosylation Reactions Article · 24 Jun 2020
- Synthesis and Structural Analysis of Aspergillus fumigatus Galactosaminogalactans Featuring α‐Galactose, α‐Galactosamine and α‐ N ‐Acetyl Galactosamine Linkages Article · 20 May 2020
- Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable In Vitro and In-Cell Site-Specific Labeling Article · 6 May 2020
- Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation Article · 18 Feb 2020
- Synthesis of N β -Substituted α,β-Diamino Acids via Stereoselective N -Michael Additions to a Chiral Bicyclic Dehydroalanine Article · 10 Feb 2020
- Selective modification of sulfamidate-containing peptides Article · 2020
- Lanthionine Peptides by S -Alkylation with Substituted Cyclic Sulfamidates Promoted by Activated Molecular Sieves: Effects of the Sulfamidate Structure on the Yield Article · 18 Oct 2019
- Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions Article · 7 Aug 2019
- Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification Article · 19 Jul 2019
- Cover Feature: Elusive Dehydroalanine Derivatives with Enhanced Reactivity (ChemBioChem 10/2019) Article · 2 May 2019
- Tetrazine‐Triggered Release of Carboxylic‐Acid‐Containing Molecules for Activation of an Anti‐inflammatory Drug Article · 29 Apr 2019
- Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation Article · 9 Apr 2019
- Elusive Dehydroalanine Derivatives with Enhanced Reactivity Article · Apr 2019
- Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage Article · 6 Feb 2019
- Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease Article · 14 Jan 2019
- Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent Book / chapter · 2019
- Azabicyclic vinyl sulfones for residue-specific dual protein labelling Article · 2019
- Oxygen by Carbon Replacement at the Glycosidic Linkage Modulates the Sugar Conformation in Tn Antigen Mimics Article · 24 Dec 2018
- Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents Article · 23 Nov 2018
- A Late-Stage Synthetic Approach to Lanthionine-Containing Peptides via S-Alkylation on Cyclic Sulfamidates Promoted by Molecular Sieves Article · 14 Nov 2018
- Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells Article · 2 Nov 2018
- Substrate-assisted enzymatic formation of lysinoalanine in duramycin Article · 3 Sep 2018
- The Conformation of the Mannopyranosyl Phosphate Repeating Unit of the Capsular Polysaccharide of Neisseria meningitidis Serogroup A and Its Carba‐Mimetic Article · 17 Aug 2018
- Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition Article · 13 Jul 2018
- Cell‐Penetrating Peptides Containing Fluorescent d ‐Cysteines Article · 8 May 2018
- Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1- S - and C1- O -Nucleophiles Article · 11 Apr 2018
- Chemo- and Regioselective Lysine Modification on Native Proteins Article · 23 Feb 2018
- The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences Article · 5 Dec 2017
- Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation Article · 5 Dec 2017
- The key role of Au-substrate interactions in catalytic gold subnanoclusters Article · 21 Nov 2017
- Substituent Effects on the Reactivity of Cyclic Tertiary Sulfamidates Article · 17 Nov 2017
- Computational Design of Protein Function Book / chapter · 2 Nov 2017
- Oxidative Activation of C–S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides Article · 28 Sep 2017
- Metal-Free [2 + 2]-Photocycloaddition of ( Z )-4-Aryliden-5(4 H )-Oxazolones as Straightforward Synthesis of 1,3-Diaminotruxillic Acid Precursors: Synthetic Scope and Mechanistic Studies Article · 24 Aug 2017
- A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst Article · 24 Aug 2017
- Multiple Mechanisms for the Thermal Decomposition of Metallaisoxazolin-5-ones from Computational Investigations Article · 2 Aug 2017
- 1,3-Dipolar Cycloaddition Reactions of Low-Valent Rhodium and Iridium Complexes with Arylnitrile N -Oxides Article · 27 Apr 2017
- Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells Article · 8 Dec 2016
- Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents Article · 26 Oct 2016
- A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells Article · 20 Oct 2016
- Tn Antigen Mimics Based on sp 2 -Iminosugars with Affinity for an anti-MUC1 Antibody Article · 25 Jul 2016
- Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S -Michael Addition Article · 1 Jun 2016
- Computations Reveal That Electron-Withdrawing Leaving Groups Facilitate Intramolecular Conjugate Displacement Reactions by Negative Hyperconjugation Article · 4 May 2016
- A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2 Article · 8 Feb 2016
- Origins of stereoselectivity in evolved ketoreductases Article · 7 Dec 2015
- Synthesis of Mixed α/β 2,2 -Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates Article · 16 Nov 2015
- Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and the Total Synthesis of (−)‐Nitidasin Article · 20 Aug 2015
- Pyridine N -Oxide vs Pyridine Substrates for Rh(III)-Catalyzed Oxidative C–H Bond Functionalization Article · 3 Aug 2015
- Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations Article · 29 Jun 2015
- Molecular Dynamics of the Diels–Alder Reactions of Tetrazines with Alkenes and N 2 Extrusions from Adducts Article · 6 Apr 2015
- Molecular Dynamics Explorations of Active Site Structure in Designed and Evolved Enzymes Article · 4 Mar 2015
- Enantioselective Synthesis of Dialkylated N -Heterocycles by Palladium-Catalyzed Allylic Alkylation Article · 25 Feb 2015
- N‐Type Conjugated Polymer‐Enabled Selective Dispersion of Semiconducting Carbon Nanotubes for Flexible CMOS‐Like Circuits Article · 13 Feb 2015
- Thermodynamic Evaluation of Aromatic CH/π Interactions and Rotational Entropy in a Molecular Rotor Article · 4 Feb 2015
- Substrate control in stereoselective lanthionine biosynthesis Article · 24 Nov 2014
- Synthesis and Conformational Analysis of Hybrid α/β‐Dipeptides Incorporating S ‐Glycosyl‐β 2,2 ‐Amino Acids Article · 20 Nov 2014
- A Twist on Facial Selectivity of Hydride Reductions of Cyclic Ketones: Twist-Boat Conformers in Cyclohexanone, Piperidone, and Tropinone Reactions Article · 5 Nov 2014
- Long-Range Distance Measurements in Proteins at Physiological Temperatures Using Saturation Recovery EPR Spectroscopy Article · 7 Oct 2014
- Cycloadditions of Cyclohexynes and Cyclopentyne Article · 5 Oct 2014
- Solvent Effects on Polymer Sorting of Carbon Nanotubes with Applications in Printed Electronics Article · 19 Aug 2014
- Experimental and Theoretical Study of Gold(III)-Catalyzed Hydration of Alkynes Article · 16 Jul 2014
- Correction to High-Yield Sorting of Small-Diameter Carbon Nanotubes for Solar Cells and Transistors Article · 2 Jul 2014
- The role of distant mutations and allosteric regulation on LovD active site dynamics Article · 13 Apr 2014
- Influence of Amino Acid Stereocenters on the Formation of Bicyclic N , O -Acetals Article · 11 Mar 2014
- Competition Between Concerted and Stepwise Dynamics in the Triplet Di‐π‐Methane Rearrangement Article · 11 Mar 2014
- An Iterative, Bimodular Nonribosomal Peptide Synthetase that Converts Anthranilate and Tryptophan into Tetracyclic Asperlicins Article · Jul 2013
- Stereochemical Outcome of Copper-Catalyzed C–H Insertion Reactions. An Experimental and Theoretical Study Article · 5 Jun 2013
- Mechanism of Alkoxy Groups Substitution by Grignard Reagents on Aromatic Rings and Experimental Verification of Theoretical Predictions of Anomalous Reactions Article · 22 Apr 2013
- Mechanistic Study of a Ru-Xantphos Catalyst for Tandem Alcohol Dehydrogenation and Reductive Aryl-Ether Cleavage Article · 16 Apr 2013
- A Dynamic Combinatorial Approach for the Analysis of Weak Carbohydrate/Aromatic Complexes: Dissecting Facial Selectivity in CH/π Stacking Interactions Article · 25 Feb 2013
- Scalable and Selective Dispersion of Semiconducting Arc-Discharged Carbon Nanotubes by Dithiafulvalene/Thiophene Copolymers for Thin Film Transistors Article · 22 Feb 2013
- Confined organization of fullerene units along high polymer chains Article · 2013
- Evaluation of several catalytic systems for the epoxidation of methyl oleate using H2O2 as oxidant Article · Nov 2012
- Forming Tertiary Organolithiums and Organocuprates from Nitrile Precursors and their Bimolecular Reactions with Carbon Electrophiles to Form Quaternary Carbon Stereocenters Article · 24 Aug 2012
- A highly efficient, green and recoverable catalytic system for the epoxidation of fatty esters and biodiesel with H2O2 Article · May 2012
- Glycerol ketals: Synthesis and profits in biodiesel blends Article · Apr 2012
- A Biomimetic Approach to Lanthionines Article · 16 Dec 2011
- A Domino Michael/Dieckmann Process as an Entry to α-(Hydroxymethyl)glutamic Acid Article · 10 Aug 2011
- Stereocontrolled Ring-Opening of a Hindered Sulfamidate with Nitrogen-Containing Aromatic Heterocycles: Synthesis of Chiral Quaternary Imidazole Derivatives Article · 28 Apr 2011
- Accurate Calculation of Chemical Shifts in Highly Dynamic H 2 @C 60 through an Integrated Quantum Mechanics/Molecular Dynamics Scheme Article · 25 Apr 2011
- Fatty acid derivatives and their use as CFPP additives in biodiesel Article · Feb 2011
- Can Enantioselectivity be Computed in Enthalpic Barrierless Reactions? The Case of Cu I ‐Catalyzed Cyclopropanation of Alkenes Article · 9 Nov 2010
- Stereoselectivity induced by support confinement effects. Aza-pyridinoxazolines: A new family of C1-symmetric ligands for copper-catalyzed enantioselective cyclopropanation reactions Article · 2010
- Steric Control of α- and β-Alkylation of Azulenone Intermediates in a Guanacastepene A Synthesis Article · 29 Dec 2009
- A Novel Multistep Mechanism for the Stereocontrolled Ring Opening of Hindered Sulfamidates: Mild, Green, and Efficient Reactivity with Alcohols Article · 23 Sep 2009
- Insights into the Geometrical Features Underlying β‐ O ‐GlcNAc Glycosylation: Water Pockets Drastically Modulate the Interactions between the Carbohydrate and the Peptide Backbone Article · 17 Jul 2009
- The unusual reactivity of benzene and monosubstituted benzenes towards tetracyanoethylene oxide: a theoretical study Article · 2009
- α-Alkylation versus retro-O-Michael/γ-alkylation of bicyclic N,O-acetals: an entry to α-methylthreonine Article · Dec 2008
- Mechanistic insights on the site selectivity in successive 1,3-dipolar cycloadditions to meso-tetraarylporphyrins Article · Aug 2008
- Non‐natural Amino Acids as Modulating Agents of the Conformational Space of Model Glycopeptides Article · 30 Jul 2008
- Surface Confinement Effects on Enantioselective Cyclopropanation. Reactions with Supported Chiral 8-Oxazolinylquinoline−Copper Complexes Article · 25 Apr 2008
- Highly chemoselective reactions on hindered sulfamidates with oxygenated nucleophiles Article · Mar 2008
- Role of the Countercation in Diastereoselective Alkylations of Pyramidalized Bicyclic Serine Enolates. An Easy Approach to α-Benzylserine. Article · 1 Aug 2007
- Serine versus Threonine Glycosylation: The Methyl Group Causes a Drastic Alteration on the Carbohydrate Orientation and on the Surrounding Water Shell Article · 7 Jul 2007
- Theoretical Evidence for Pyramidalized Bicyclic Serine Enolates in Highly Diastereoselective Alkylations Article · 22 May 2007
- QM/MM Modeling of Enantioselective Pybox–Ruthenium‐ and Box–Copper‐Catalyzed Cyclopropanation Reactions: Scope, Performance, and Applications to Ligand Design Article · 26 Apr 2007
- Mechanistic study of the ring-size modulation in Michael–Dieckmann type reactions of 2-acylaminoacrylates with ketene diethyl acetal Article · 2007
- New Insights into α-GalNAc−Ser Motif: Influence of Hydrogen Bonding versus Solvent Interactions on the Preferred Conformation Article · 25 Oct 2006
- Stereoselective Synthesis of Orthogonally Protected α-Methylnorlanthionine Article · 20 May 2006
- Conformational Analysis of 2-Substituted Cyclobutane-α-amino Acid Derivatives. A Synergistic Experimental and Computational Study Article · 1 Feb 2006
- S N 2 Reaction of Sulfur Nucleophiles with Hindered Sulfamidates: Enantioselective Synthesis of α-Methylisocysteine Article · 13 Jan 2006
- Enantioselective Synthesis of S -Linked Glycosyl-β 2,2 -Amino Acid Derivatives by S N 2 Reaction with Hindered Sulfamidates Article · 2006
- A Convenient Enantioselective Synthesis of ( S )-α-Trifluoromethylisoserine Article · 15 Jun 2005
- S N 2 vs E2 on Quaternary Centers: An Easy Approach to Chiral β 2 , 2 -Amino Acids from Cyclic Sulfamidates Article · 2 Mar 2005
- New syntheses of enantiopure 2-methyl isoserines Article · Jan 2004
- S N 2 vs. E2 on quaternary centres: an application to the synthesis of enantiopure β 2,2 -amino acids Article · 2004
- Conformational analysis of N-Boc-N,O-isopropylidene-α-serinals. A combined DFT and NMR study Article · Jul 2003