Detalle de: Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus
| Title | Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus |
| Abstract |
Amphibian-like ranaviruses include pathogens of fish, amphibians, and reptiles that have recently evolved from a fish-infecting ancestor. The molecular determinants of host range and virulence in this group are largely unknown, and currently fish infection models are lacking. We show that European sheatfish virus (ESV) can productively infect zebrafish, causing a lethal pathology, and describe a method for the generation of recombinant ESV, establishing a useful model for the study of fish ranavirus infections. |
| Apa Reference | Martín, V., Mavian, C., López Bueno, A., de Molina, A., Díaz, E., Andrés, G., Alcami, A. & Alejo, A. (2015). Establishment of a Zebrafish Infection Model for the Study of Wild-Type and Recombinant European Sheatfish Virus. Journal of Virology, 89(20), 10702-10706. 10.1128/jvi.01580-15 |
| Doi | 10.1128/jvi.01580-15 |
| Publication Date | 15 Oct 2015 |
| Publication Type | Article |
| Researcher | Antonio Alcamí |
| Ontology | Model organisms |
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| Tools |