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Detalle de: Receptors for gamma-interferon encoded by poxviruses: implications for the unknown origin of vaccinia virus

Title Receptors for gamma-interferon encoded by poxviruses: implications for the unknown origin of vaccinia virus
Abstract

Poxviruses encode soluble interferon-gamma receptors (IFN-gamma Rs) that inhibit IFN-gamma activity and play a major role in virus pathogenesis. In contrast to the highly species specific cellular homologues, the vaccinia IFN-gamma R has novel broad species specificity. This has implications for the unknown origin and natural host(s) of vaccinia virus, the vaccine used for smallpox eradication.

Apa Reference Alcamí, A. & Smith, G.L. (1996). Receptors for gamma-interferon encoded by poxviruses: implications for the unknown origin of vaccinia virus. Trends in Microbiology, 4(8), 321-326. 10.1016/0966-842X(96)10051-2
Doi 10.1016/0966-842X(96)10051-2
Publication Date Aug 1996
Publication Type Article
Researcher Antonio Alcamí
Ontology
Research Groups
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