Detalle de: OMICS TECHNOLOGIES AND NEW COMPUTATIONAL CHALLENGES

In recent years, omics technologies have become common practice in the field of neuroscience. Multiple cell types coexist and interact in brain tissue, defined not only by their function but also by their anatomical position and connection with other cells in other brain regions. For this reason, the Ci2A Bioinformatics Unit was created as an NGS and bioinformatics analysis service specialized in the study of the brain, both in its anatomy and cellular diversity, as well as its functionality. This poses a challenge within bioinformatics when it comes to developing the algorithms necessary to identify each of the cell types that make up a tissue and developing analytical methods that allow for the analysis of the processes that occur within them under basal conditions or in pathological states. The aim is to develop the analysis of single-cell experiments and spatial transcriptomics from different brain regions to study in depth the different cell types that make up the heterogeneity of brain tissue and the interconnections between them.