Jaime Pignatelli
Biography
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Dr. Pignatelli got a PhD in Molecular Biology from the Madrid Autonoma de Madrid. He is the person in charge of the Omics and Bioinformatics Unit and the Neuroendrocrinology laboratory at the Cajal Center for Neuroscience CSIC. He also participates on the CSIC PTI Neuroaging+. He has published more than 30 articles in peer reviewed scientific journals, and has supervised 1 doctoral thesis, as well as, TFM and TFG works. |
Profile
| Institution | IC |
| Position | Unit responsible |
| Home page | https://www.linkedin.com/in/jpignatelligarrigos/ |
| Contact email | jpigna@cajal.csic.es |
| ORCID | 0000-0002-8431-2241 |
BCB Hub
| BCB Committee | Not a member |
| BCB Tools | |
| BCB Services | Bioinformatics unit at IC |
Research
Research topics
OmicsComputational MethodsResourcesTranscriptomicsRNA Sequencing (RNA-seq)Data AnalysisArtificial IntelligenceMachine Learning in BiologyBioinformatics Software and ToolsAnalysis packages (R, Python, etc.)Data VisualizationApplications of Computational Biology
View all (27 more)
Model organismsBioinformatics enabling techniquesStandards in Computational BiologyBenchmarkingGenomicsGenome SequencingFunctional genomicsExpression ProfilingComputational models and simulationsGene regulatory networksVariant callingEpigenomicsDNA methylationStatistical Methods for BiologyBioinformatics educationChromatin accessibilityExperimental designPathway analysisMultivariate statisticsSingle-cell omicsSingle-cell (scRNA-seq)DevelopmentBayesian statisticsNon-parametric statisticsDeep Learning in BiologyAnimal genomicsSpatial transcriptomics
Research lines
Projects, networks, transfer & teaching
Funded projects 1
Publications 37 entries
- Lighting Up Mislocalized Proteins: Quantum Dot Probes for Multiplexed Cytoplasm-Selective Cell Profiling in Neurodegeneration Article · 21 May 2026
- Influence of Lifestyle on Brain Sensitivity to Circulating Insulin-like Growth Factor 1 Article · 14 Oct 2025
- Nanoparticles targeting the central circadian clock: Potential applications for neurological disorders☆ Article · May 2025
- Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance Article · 6 May 2024
- A role for astrocytic insulin-like growth factor I receptors in the response to ischemic insult Article · 28 Nov 2023
View all (32 more)
- The Role of Insulin-like Growth Factor I in Mechanisms of Resilience and Vulnerability to Sporadic Alzheimer's Disease Article · 17 Nov 2023
- The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states Article · 23 Jun 2023
- Transgenerational effects of exercise on mouse brain and cognition Preprint · 10 Mar 2023
- Insulin regulates neurovascular coupling through astrocytes Article · 14 Jul 2022
- Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex Article · 4 Jul 2022
- Morphological Diversity of Calretinin Interneurons Generated From Adult Mouse Olfactory Bulb Core Neural Stem Cells Article · 29 Jun 2022
- Insulin-like growth factor I sensitization rejuvenates sleep patterns in old mice Article · 23 May 2022
- Insulin-like Growth Factor I Couples Metabolism with Circadian Activity through Hypothalamic Orexin Neurons Article · 23 Apr 2022
- Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons Article · 3 Feb 2022
- Astrocytic IGF-IRs Induce Adenosine-Mediated Inhibitory Downregulation and Improve Sensory Discrimination Article · 28 Apr 2021
- Circulating Insulin-Like Growth Factor I is Involved in the Effect of High Fat Diet on Peripheral Amyloid β Clearance Article · 18 Dec 2020
- Insulin-like growth factor I modulates sleep through hypothalamic orexin neurons Article · 8 Oct 2020
- IGF-I Governs Cortical Inhibitory Synaptic Plasticity By Astrocyte Activation Preprint · 12 Feb 2020
- Insulin-Like Growth Factor I Modulates Vulnerability to Stress Through Orexin Neurons Preprint · 10 Feb 2020
- Cell-specific expression of insulin/insulin-like growth factor-I receptor hybrids in the mouse brain Article · Apr 2019
- Characterization of BAFF and APRIL subfamily receptors in rainbow trout (Oncorhynchus mykiss). Potential role of the BAFF/APRIL axis in the pathogenesis of proliferative kidney disease Article · 21 Mar 2017
- SYNTHESIS OF CYCLOBUTANE NUCLEOSIDES 2-PREPARATION OF THYMINE AND URACIL ANALOGUES Article · 23 Sep 2015
- Identification of Teleost Skin CD8 alpha(+) Dendritic-like Cells, Representing a Potential Common Ancestor for Mammalian Cross-Presenting Dendritic Cells Article · Aug 2015
- Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes Article · Jul 2015
- Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes Article · 10 Dec 2014
- Early Immune Responses in Rainbow Trout Liver upon Viral Hemorrhagic Septicemia Virus (VHSV) Infection Article · 22 Oct 2014
- Immunological Characterization of the Teleost Adipose Tissue and Its Modulation in Response to Viral Infection and Fat-Content in the Diet Article · 21 Oct 2014
- CCR7 Is Mainly Expressed in Teleost Gills, Where It Defines an IgD(+)IgM(-) B Lymphocyte Subset Article · 1 Feb 2014
- Transcriptional Heterogeneity of IgM(+) Cells in Rainbow Trout (Oncorhynchus mykiss) Tissues Article · 6 Dec 2013
- Lineage specific antigenic differences in porcine torovirus hemagglutinin-esterase (PToV-HE) protein Article · Dec 2013
- Transcriptional Regulation of Olfactory Bulb Neurogenesis Article · 31 Jul 2013
- A Global Transcriptome Analysis Reveals Molecular Hallmarks of Neural Stem Cell Death, Survival, and Differentiation in Response to Partial FGF-2 and EGF Deprivation Article · 7 Jan 2013
- Seroprevalence of porcine torovirus (PToV) in Spanish farms Article · Dec 2012
- Longitudinal serological and virological study on porcine torovirus (PToV) in piglets from Spanish farms Article · Dec 2010
- Detection of porcine torovirus by real time RT-PCR in piglets from a Spanish farm Article · Feb 2010
- Molecular characterization of a new PToV strain. Evolutionary implications Article · Jul 2009
- New insights on the structure and morphogenesis of Berne virus Book / chapter · 2006