Irene Otero-Muras
Computational Synthetic Biology · I2SYSBIO
Associated Unit I2SYSBIO - CRM · I2SYSBIO
Biography
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Chemical engineer by training, I did my PhD in applied mathematics at the BioProcess Engineering Group (CSIC) under the supervision of Antonio A. Alonso and Julio R. Banga. Since the beginning of my scientific career I was interested in understanding the complex dynamic behavior of biomolecular networks and its connection with relevant biological functions. During my postdoc at ETH (D-BSSE) with J Stelling, I became familiar with the open questions and challenges in systems and synthetic biology. Back at CSIC I started my work on the automated design of biocircuits for synthetic biology and on efficient methods for stochastic modeling and simulation of gene regulatory networks, helping to provide insight on cellular decisions under stochastic noise. One of my fundamental research aims is to understand the role of molecular noise in relevant cellular functions and exploit this knowledge for the advanced design, analysis and control of biosystems. |
Profile
| Institution | I2SYSBIO |
| Position | Científica Titular |
| Home page | https://noisynbio.org |
| Contact email | irene.otero.muras@csic.es |
| ORCID | 0000-0003-2895-997X |
BCB Hub
| BCB Committee | Not a member |
| BCB Tools | SYNBADm |
| BCB Services |
Research
Research topics
Research lines
None
Projects, networks, transfer & teaching
Funded projects 1
Publications 17 entries
- Engineering phenotypic heterogeneity for functional organization in microbial populations Preprint · 15 Sep 2026
- BiosInt: Biosensor-based smart design of pathway dynamic regulation for industrial biomanufacturing Preprint · 17 Nov 2025
- A Computational Framework for Optimal and Model Predictive Control of Stochastic Gene Regulatory Networks Article · Nov 2025
- Stochastic SIR model predicts the evolution of COVID-19 epidemics from public health and wastewater data in small and medium-sized municipalities: A one year study Article · Nov 2022
- Automated design of gene circuits with optimal mushroom-bifurcation behaviour Preprint · 10 May 2022
View all (12 more)
- Wastewater and Marine Bioindicators Surveillance to Anticipate COVID-19 Prevalence and to Explore SARS-CoV-2 Diversity by Next Generation Sequencing: One-Year Study Preprint · 2021
- A general technique for the detection of switch-like bistability in chemical reaction networks governed by mass action kinetics with conservation laws Preprint · 8 Nov 2020
- Solving the Competitive Binding Equilibria between Many Ligands: Application to High-Throughput Screening and Affinity Optimization Article · 19 Aug 2020
- Transient hysteresis and inherent stochasticity in gene regulatory networks Article · 8 Oct 2019
- Routes to Multiple Equilibria for Mass‐Action Kinetic Systems Article · Jan 2018
- Chemical Reaction Network Theory elucidates sources of multistability in interferon signaling Article · 3 Apr 2017
- Advances in Chemical Reaction Network Theory for the Identification of Kinetic Models Article · Jul 2012
- Inducing sustained oscillations in mass action kinetic networks of a certain class Article · 2012
- Contributing to fisheries sustainability by making the best possible use of their resources: the BEFAIR initiative Article · Nov 2010
- Dynamic analysis and control of biochemical reaction networks Article · Dec 2008
- Local dissipative Hamiltonian description of reversible reaction networks Article · Jul 2008
- A systematic approach to plant-wide control based on thermodynamics Article · May 2007