Angela Nieto Toledano
Biography
|
Analysis of cell movements and cell plasticity in health and disease. Our group studies the regulation of epithelial-mesenchymal transitions (EMT) during vertebrate embryonic development and in several pathologies including cancer and fibrosis. |
Profile
| Institution | IN |
| Position | CSIC Research Professor, Group Leader |
| Home page | https://in.umh-csic.es/es/author/anietoumh-es/ |
| Contact email | anieto@umh.es |
| ORCID | 0000-0002-3538-840X |
BCB Hub
| BCB Committee | Future Plan |
| BCB Tools | |
| BCB Services |
Research
Research topics
TranscriptomicsModel organismsGene regulatory networksMolecular evolutionDevelopmentGenome editing (CRISPR)
Research lines
Publications 82 entries
- Decoding epithelial–mesenchymal transitions with multi-omics Article · 5 Oct 2026
- Epithelial-to-mesenchymal transition as a central driver of tumor cell plasticity Article · 24 Apr 2026
- A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential Article · 4 Mar 2026
- From embryos to cancer Article · 5 Jan 2026
- Mutual repression between Pax2 and Snail factors regulates the epithelial/mesenchymal state during intermediate mesoderm differentiation Article · 15 Aug 2025
View all (77 more)
- Melanoma innervation, noradrenaline and cancer progression in zebrafish xenograft model Article · 31 May 2025
- Epithelial–mesenchymal transition in tissue repair and degeneration Article · 29 Apr 2024
- Publisher Correction: Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche Article · 24 Apr 2024
- Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche Article · 2 Apr 2024
- Microenvironmental Snail1-induced immunosuppression promotes melanoma growth Article · 29 Jul 2023
- Antifibrotic drugs as therapeutic tools in resistant melanoma Article · 14 Feb 2022
- Proliferation and EMT trigger heart repair Article · 12 Oct 2020
- In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition Article · 7 Oct 2020
- Reply to: Zebrafish prrx1a mutants have normal hearts Article · 23 Sep 2020
- A gene regulatory network to control EMT programs in development and disease Article · 11 Nov 2019
- The Evolutionary History of Ephs and Ephrins: Toward Multicellular Organisms Article · 7 Oct 2019
- Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease Article · 8 May 2019
- EMT in cancer Article · 12 Jan 2018
- A snail tale and the chicken embryo Article · 2018
- A right-handed signalling pathway drives heart looping in vertebrates Article · 7 Sep 2017
- Upholding a role for EMT in breast cancer metastasis Article · 6 Jul 2017
- Upholding a role for EMT in pancreatic cancer metastasis Article · Jul 2017
- Snail2 and Zeb2 repress P-cadherin to define embryonic territories in the chick embryo Article · 15 Feb 2017
- Identification of p53-target genes in Danio rerio Article · 1 Sep 2016
- EMT: 2016 Article · Jun 2016
- Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease Article · 3 Aug 2015
- Molecular Mechanisms Controlling the Migration of Striatal Interneurons Article · 10 Jun 2015
- eEF1A Mediates the Nuclear Export of SNAG-Containing Proteins via the Exportin5-Aminoacyl-tRNA Complex Article · Aug 2014
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells Article · 8 Nov 2013
- Scratch2 Prevents Cell Cycle Re-Entry by Repressing miR-25 in Postmitotic Primary Neurons Article · 20 Mar 2013
- Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1 Article · Dec 2012
- The epithelial–mesenchymal transition under control: Global programs to regulate epithelial plasticity Article · Oct 2012
- Mutual exclusion of transcription factors and cell behaviour in the definition of vertebrate embryonic territories Article · Aug 2012
- The endogenous retrovirus ENS-1 provides active binding sites for transcription factors in embryonic stem cells that specify extra embryonic tissue Article · 15 Mar 2012
- The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease Article · 10 Nov 2011
- Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation Article · 27 Sep 2011
- Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation Article · Sep 2011
- An Epigenetic Mark that Protects the Epithelial Phenotype in Health and Disease Article · May 2011
- Repression of Puma by Scratch2 is required for neuronal survival during embryonic development Article · 21 Jan 2011
- Thanatophoric dysplasia type II with encephalocele and semilobar holoprosencephaly: Insights into its pathogenesis Article · 28 Dec 2010
- O2. The antagonism between Sox3 and Snail control cell movements to define the ectodermal/mesendodermal boundary in vertebrates Article · Nov 2010
- Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes Article · 15 Oct 2010
- Epithelial plasticity, stemness and pluripotency Article · 7 Sep 2010
- Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice Article · Mar 2010
- Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia Article · 23 Dec 2009
- Epithelial-Mesenchymal Transitions in Development and Disease Article · Nov 2009
- Inflammation and EMT: an alliance towards organ fibrosis and cancer progression Article · 28 Sep 2009
- 13-P126 scratch2 antagonizes p53-mediated apoptosis in the zebrafish spinal cord Article · Aug 2009
- Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease Article · 1 Jun 2009
- Evolutionary history of the Snail/Scratch superfamily Article · Jun 2009
- Ectopic expression of Cvh (Chicken Vasa homologue) mediates the reprogramming of chicken embryonic stem cells to a germ cell fate Article · Jun 2009
- Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A Article · 15 May 2009
- Characterization of Snail nuclear import pathways as representatives of C2H2 zinc finger transcription factors Article · 1 May 2009
- The class I bHLH factors E2-2A and E2-2B regulate EMT Article · 1 Apr 2009
- Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation Article · 5 Feb 2009
- Epithelial-Mesenchymal Transitions in development and disease: old views and new perspectives Article · 2009
- Riding the right wave: would the real neural crest please stand up? Article · Sep 2008
- Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition Article · Aug 2008
- A new regulatory loop in cancer‐cell invasion Article · 16 May 2008
- The physiology and pathology of the EMT Article · 7 Mar 2008
- Les gènes Snail et les maladies rénales Article · Mar 2008
- Chapter 9 In Situ Hybridization Analysis of Chick Embryos in Whole‐Mount and Tissue Sections Book / chapter · 2008
- Snail1 Is a Transcriptional Effector of FGFR3 Signaling during Chondrogenesis and Achondroplasias Article · Dec 2007
- Snail genes at the crossroads of symmetric and asymmetric processes in the developing mesoderm Article · 24 Nov 2006
- Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney Article · 9 Nov 2006
- The expression of Scratch genes in the developing and adult brain Article · 13 Jun 2006
- How to become neural crest: From segregation to delamination Article · Dec 2005
- A molecular role for lysyl oxidase‐like 2 enzyme in Snail regulation and tumor progression Article · 18 Aug 2005
- The Snail genes as inducers of cell movement and survival: implications in development and cancer Article · 15 Jul 2005
- Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability Article · Jul 2005
- LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest Article · 15 Sep 2004
- Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo Article · 1 Jun 2004
- Snail blocks the cell cycle and confers resistance to cell death Article · 15 May 2004
- Expression of chicken slug and snail in mesenchymal components of the developing central nervous system Article · 31 Mar 2004
- Snail family members and cell survival in physiological and pathological cleft palates Article · Jan 2004
- Relative expression of Slug, RhoB, and HNK‐1 in the cranial neural crest of the early chicken embryo Article · 10 Dec 2003
- Snail3 orthologues in vertebrates: divergent members of the Snail zinc-finger gene family Article · 4 Dec 2003
- Snail precedes Slug in the genetic cascade required for the specification and migration of the Xenopus neural crest Article · 1 Feb 2003
- Modularity and reshuffling of Snail and Slug expression during vertebrate evolution Article · 13 Dec 2002
- Biological Potential of a Functional Human SNAILRetrogene Article · Oct 2002
- The snail superfamily of zinc-finger transcription factors Article · Mar 2002
- Progressive Spatial Restriction ofSek-1andKrox-20Gene Expression during Hindbrain Segmentation Article · Jan 1996