Ian Morilla
Plant-virus interaction · IHSM
Machine Learning in Multi-Omics (MLiMO) · IHSM
Biography
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Ian Morilla leads the Machine Learning in Multi Omics (MLiMO) group at the Instituto de Hortofruticultura Subtropical y Mediterránea "La Mayora" (IHSM, UMA-CSIC) since 2023, and is a member of the Mathématiques pour la Biologie et les Images (MBI) team at the Laboratoire Analyse, Géométrie et Applications (LAGA, CNRS-Université Sorbonne Paris Nord) since 2018. At MLiMO, we harness advanced machine learning and integrative multi-omics approaches to unravel the complexity of biological systems. Our interdisciplinary research spans from fundamental questions in tumour micro-environments to dynamic modelling in plant and human diseases. Through robust data-driven methodologies, we uncover the principles that orchestrate life’s molecular networks—translating insights into advances for precision medicine, sustainable agriculture, and beyond. (Description curated from publicly available data.) |
Profile
| Institution | IHSM |
| Position | Advanced Research Associate |
| Home page | https://mlimowebsite.faculty.bio/ |
| Contact email | ian.morilla@ihsm.uma-csic.es |
| ORCID | 0000-0002-5100-5990 |
BCB Hub
| BCB Committee | Outreach, Talent attraction and training |
| BCB Tools | S²-PepAnalyst, TaelCore, CoMM-BIP, GeoTop |
| BCB Services |
Research
Research topics
OmicsComputational MethodsData AnalysisArtificial IntelligenceMachine Learning in BiologyApplications of Computational BiologyLarge language modelsFunctional genomicsFunction predictionComputational models and simulationsGene regulatory networksPersonal medicine
View all (13 more)
Systems BiologyIntegrative AnalysisRegulatory biologyStatistical Methods for BiologyPathway analysisPlant genomicsImage analysisNetwork BiologyMicrobial communitiesDeep Learning in BiologyClinical dataSpatial transcriptomicsDimensionality reduction
Research lines
Projects, networks, transfer & teaching
Industry & knowledge transfer
Patents
- Methods for predicting acute severe colitis treatment response (Medical Kits), 17340534-Issued.
- Methods for predicting acute severe colitis treatment response (DeepCol Software), US11060147B2-Issued.
Teaching
Master programs
- Master de mathématiques de données et IA - Université Sorbonne Paris Nord
Funded projects 5
- Decoding vector-induced gene regulation in plant-insect-virus causal diagrams
- Charting the shared basis of Cancer, Autoimmune, and Cardiovascular diseases using multi-scale Topology and Optimal Transport
- TRANSCEND-ID. Approches intégratives d’Intelligence Artificielle et de la biologie pour la modélisation de l'inflammation chronique
- Computational identification of small signalling peptides
View all (1 more)
Publications 36 entries
- Topological Deep Learning Identifies Polygenic Variant Clusters Across Familial Multimorbid Disorders Preprint · 9 Jun 2026
- Foundational characterization of tomato fruit RALF peptides reveals structural and functional specialization within the SlRALF family Preprint · 6 Jun 2026
- Early identification of high-risk individuals for mortality after lung transplantation: A retrospective cohort study with topological feature engineering Article · 5 May 2026
- S 2 ‐ PepAnalyst : A Web Tool for Predicting Plant Small Signalling Peptides Article · 28 Jan 2026
- Arabidopsis lines with modified ascorbate concentrations reveal a link between ascorbate and auxin biosynthesis Article · 23 Dec 2025
View all (31 more)
- Multimodal Learning Reveals Plants’ Hidden Sensory Integration Logic Preprint · 27 Jul 2025
- Multimodal Learning Reveals Plants' Hidden Sensory Integration Logic Software · 21 Jul 2025
- Novel dimensionality reduction method, Taelcore, enhances lung transplantation risk prediction Software · Feb 2024
- The Genotypic Imperative: Unraveling Disease-Permittivity in Functional Modules of Complex Diseases Article · 11 Dec 2023
- Plasma proteome dynamics of COVID-19 severity learnt by a graph convolutional network of multi-scale topology Article · 20 Feb 2023
- Security of Android Banking Mobile Apps: Challenges and Opportunities Book / chapter · 2023
- Personalized risk predictor for acute cellular rejection in lung transplant using soluble CD31 Article · 21 Oct 2022
- Deciphering the Dynamic Molecular Program of Radiation-Induced Endothelial Senescence Article · Mar 2022
- Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation Article · Jan 2022
- Process-Oriented Intents: A Cornerstone for Superimposition of Natural Language Conversations over Composite Services Book / chapter · 2022
- Computational learning of microRNA-based prediction of pouchitis outcome after restorative proctocolectomy in patients with ulcerative colitis Article · 20 Feb 2021
- Singular manifolds of proteomic drivers to model the evolution of inflammatory bowel disease status Article · 4 Nov 2020
- A deep learning approach to evaluate intestinal fibrosis in magnetic resonance imaging models Article · 16 Mar 2020
- Plane Spanning Trees in Edge-Colored Simple Drawings of $$K_{n}$$ Book / chapter · 2020
- A Review of Self-balancing Robot Reinforcement Learning Algorithms Book / chapter · 2020
- Colonic MicroRNA Profiles, Identified by a Deep Learning Algorithm, That Predict Responses to Therapy of Patients With Acute Severe Ulcerative Colitis Article · Apr 2019
- In silico prediction of targets for anti-angiogenesis and their in vitro evaluation confirm the involvement of SOD3 in angiogenesis Article · 3 Apr 2018
- Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22 Article · 12 May 2017
- Mathematical deconvolution uncovers the genetic regulatory signal of cancer cellular heterogeneity on resistance to paclitaxel Article · 6 Apr 2017
- Topological Modelling of Deep Ulcerations in Patients with Ulcerative Colitis Article · 2017
- Scores of Intestinal Fibrosis from Wavelet-Based Magnetic Resonance Imaging Models Book / chapter · 2017
- Increased Proliferation of the Ileal Epithelium as a Remote Effect of Ulcerative Colitis Article · Oct 2016
- FUN-L: gene prioritization for RNAi screens Article · 8 Feb 2015
- Protein–Protein Interfaces from Cytochrome c Oxidase I Evolve Faster than Nonbinding Surfaces, yet Negative Selection Is the Driving Force Article · 29 Oct 2014
- Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation Article · 15 Aug 2014
- Novel Angiogenic Functional Targets Predicted through “Dark Matter” Assessment in Protein Networks Book / chapter · 2012
- Systematic computational prediction of protein interaction networks Article · 13 May 2011
- The function of histamine receptor H4R in the brain revealed by interaction partners Article · 2011
- Assessment of protein domain fusions in human protein interaction networks prediction: Application to the human kinetochore model Article · Dec 2010
- Finding the “Dark Matter” in Human and Yeast Protein Network Prediction and Modelling Article · 23 Sep 2010
- GeoTop: Advancing Image Classification with Geometric-Topological Analysis Article