GWideCodeML
GWideCodeML is a Python package designed to facilitate genome-wide testing of evolutionary hypotheses using codeml, a tool from the PAML (Phylogenetic Analysis by Maximum Likelihood) package. While codeml is widely used for detecting positive selection at the molecular level, it traditionally operates on a gene-by-gene basis, which limits its scalability for large genomic datasets. GWideCodeML addresses this by enabling parallelized, automated analysis across many genes and taxa.
Basic Information
| Repository | https://github.com/lauguma/gwidecodeml |
| Documentation | https://github.com/lauguma/GWideCodeML/wiki |
| Main publication (DOI) | 10.1534/g3.120.401874 view |
| Contact email | christina.toft@csic.es |
| Authors/Maintainers | Christina Toft |
| Type of application | R/python package |
| Programming languages | Python |
| Keywords | Omics, Computational Methods, Resources, Bioinformatics Software and Tools, Analysis packages (R, Python, etc.), Genomics, Molecular evolution, Evolutionary rates |
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| Type of containerization | Conda |
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| Citations (last 12 months) | <100 (~3 as of 15/10/2026) |
| Citations (since first release) | <100 (21 as of 15/10/2026) |
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